meta
|
Preg
- medecines during pregnancy KB
Search
Fluvoxamine
Overall results
Study description
Excluded studies
Table
Graphic
auto
during pregnancy (anytime or not specified)
1st trimester
2nd trimester
3rd trimester
2nd and/or 3rd trimester
throughout pregnancy
early pregnancy
days before delivery
late pregnancy
preconception-only
periconceptional
preconceptional for kinetic reason
at least 1st trimester
3 months (or more) before pregnancy or during pregnancy
1st and 2nd trimester
3 months or more before pregnancy or1st trimester
Paternal exp. genotoxic window only (0–3 months preconception)
Paternal exposure: epigenetic window only (3–xxx months preconception)
Paternal exposure: genotoxic/epigenetic window (0–xxx months preconception)
Paternal exposure: other window
Whatever the period exposition
individual studies
Outcome
TE
95% CI
n cases
n exposed
k
Pub. bias
Congenital malformations
All congenital malformations (majors, minors, majors and minors, or unspecified)
Källén, 2007 Oberlander, 2008 Einarson, 2009 Furu, 2015 Bérard, 2017
5
0.77
[
0.48
; 1.25]
116,016
519
not evaluable
Major congenital malformations
Oberlander, 2008 Einarson, 2009 Furu, 2015 Bérard, 2017
4
0.75
[
0.45
; 1.24]
74,781
481
not evaluable
Congenital heart defects
Oberlander, 2008 Malm, 2011 Bérard, 2017
3
1.15
[
0.49
; 2.69]
8,651
414
not evaluable
Limb defects
Malm, 2011 Bérard, 2017
2
0.83
[
0.31
; 2.23]
-
295
not evaluable
Nervous system anomalies
Malm, 2011 Bérard, 2017
2
2.37
[
0.75
; 7.46]
-
295
not evaluable
Atrial septal defect
Malm, 2011
1
1.02
[
0.06
; 16.42]
1,279
240
not evaluable
Cardiac septal defects
Bérard, 2017
1
2.10
[
0.51
; 8.68]
-
55
not evaluable
Digestive system anomalies
Malm, 2011
1
1.35
[
0.19
; 9.62]
-
240
not evaluable
Respiratory system anomalies
Malm, 2011
1
2.86
[
0.39
; 20.85]
-
240
not evaluable
Transposition of the great vessels
Malm, 2011
1
5.50
[
0.34
; 88.45]
238
240
not evaluable
Ventricular septal defect
Malm, 2011
1
0.42
[
0.06
; 2.97]
5,466
240
not evaluable
Maternal consequences
Gestational diabetes
Dandjinou, 2019
1
1.01
[
0.50
; 2.04]
20,905
78
not evaluable
Preeclampsia
De Vera, 2012
1
1.71
[
0.20
; 14.61]
1,216
-
not evaluable
Neonatal disorders
Neonatal death (< 28 days of life)
0
-
-
-
-
-
Persistent pulmonary hypertension
Kieler, 2012
1
3.68
[
0.23
; 59.14]
1,935
112
not evaluable
Long term consequences
Child/Infant death (> 28 days of life)
Colvin, 2012
1
1.89
[
0.60
; 5.95]
1,049
-
not evaluable
Intrauterine deaths
Early intrauterine deaths (< 22 weeks) / Spontaneous abortions
Yaris, 2005 Nakhai-Pour, 2010
2
2.36
[
0.94
; 5.95]
5,134
9
not evaluable
Late intrauterine deaths (> 22 weeks) / Stillbirths
0
-
-
-
-
-
Neuro-developmental disorders
ASD (Autism spectrum disorder): Diagnosis
Bérard, 2016
1
7.30
[
0.30
; 177.69]
1,005
35
not evaluable
ASD (Autism spectrum disorder): Diagnosis/Risk
Bérard, 2016
1
7.30
[
0.30
; 177.69]
1,005
35
not evaluable
Cognitive developmental disorders/delay (3-6 years old)
0
-
-
-
-
-
0.0
100.0
1.0
