metaPreg - Econazole during pregnancy

Econazole updated on 01-29-2025

Table Graphic exposition period:

Adverse outcome	OR 95%CI	I2	k	No. cases	No. exposed	publication bias	ROB	E-value
Congenital malformations
Cleft lip with or without cleft palate	1.85 [0.42, 8.18]	0%	2 studies	2,460	22	not evaluable	ROB	-
Congenital heart defects	2.50 [0.97, 6.43]	1%	2 studies	7,528	26	not evaluable	ROB	-
Hypospadias	2.79 [0.96, 8.13]	0%	2 studies	3,814	24	not evaluable	ROB	-
Neural Tube Defects	2.97 [0.77, 11.52]	0%	2 studies	1,952	22	not evaluable	ROB	-
All congenital malformations (majors, minors, majors and minors, or unspecified)	1.40 [0.69, 2.85]	-	1 study	22,843	34	not evaluable	ROB	-
Ano-rectal atresia and stenosis	7.63 [0.31, 187.87]	-	1 study	209	1	not evaluable	ROB	-
Bilateral renal agenesis including Potter syndrome	9.45 [0.57, 157.50]	-	1 study	104	19	not evaluable	ROB	-
Club foot / Talipes equinovarus	0.90 [0.11, 7.42]	-	1 study	2,424	20	not evaluable	ROB	-
Craniosynostosis	3.56 [0.14, 87.59]	-	1 study	447	1	not evaluable	ROB	-
Diaphragmatic hernia	5.80 [0.24, 142.60]	-	1 study	275	1	not evaluable	ROB	-
Gastroschisis	3.50 [0.14, 86.05]	-	1 study	455	1	not evaluable	ROB	-
Major congenital malformations	1.40 [0.69, 2.85]	-	1 study	22,843	34	not evaluable	ROB	-
Polydactyly	1.10 [0.12, 9.90]	-	1 study	1,744	20	not evaluable	ROB	-
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