metaPreg - Pantoprazole during pregnancy

Pantoprazole updated on 08-08-2023

Table Graphic exposition period:

Adverse outcome	OR 95%CI	I2	k	No. cases	No. exposed	publication bias	ROB	E-value
Congenital malformations
All congenital malformations (majors, minors, majors and minors, or unspecified)	1.28 [0.83, 1.99]	0%	2 studies	21,919	591	not evaluable	ROB	-
Major congenital malformations	1.28 [0.83, 1.99]	0%	2 studies	21,919	591	not evaluable	ROB	-
Growth parameters and prematurity
Adverse outcome	OR 95%CI	I2	k	No. cases	No. exposed	publication bias	ROB	E-value
Low birth weight (< 2500g)	1.05 [0.95, 1.16]	-	1 study	104,454	6,180	not evaluable	ROB	-
Preterm (< 37 weeks)	1.30 [0.57, 2.99]	-	1 study	93	48	not evaluable	ROB	-
Intrauterine deaths
Adverse outcome	OR 95%CI	I2	k	No. cases	No. exposed	publication bias	ROB	E-value
Early intrauterine deaths (< 22 weeks) / Spontaneous abortions	0.27 [0.04, 1.98]	-	1 study	59	53	not evaluable	ROB	-
Ectopic pregnancy	-	-	0 study					-
Elective/induced termination of pregnancy	1.87 [0.55, 6.37]	-	1 study	30	53	not evaluable	ROB	-
Late intrauterine deaths (> 22 weeks) / Stillbirths	8.33 [0.74, 93.34]	-	1 study	3	53	not evaluable	ROB	-
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