metaPreg - Hydrochlorothiazide (versus unexposed) during pregnancy

Hydrochlorothiazide (versus unexposed) updated on 03-11-2025

Table Graphic exposition period:

Adverse outcome	OR 95%CI	I2	k	No. cases	No. exposed	publication bias	ROB	E-value
Congenital malformations
Hypospadias	0.99 [0.23, 4.24]	-	1 study	2,131	10	not evaluable	ROB	-
Neural Tube Defects	4.30 [0.42, 43.94]	-	1 study	1,202	2	not evaluable	ROB	-
Oesophageal atresia with or without tracheo-oesophageal fistula	1.61 [0.03, 81.55]	-	1 study	221		not evaluable	ROB	-
Growth parameters and prematurity
Adverse outcome	OR 95%CI	I2	k	No. cases	No. exposed	publication bias	ROB	E-value
Small for gestational age (weight)	2.17 [0.22, 21.55]	-	1 study	5	10	not evaluable	ROB	-
Maternal consequences
Adverse outcome	OR 95%CI	I2	k	No. cases	No. exposed	publication bias	ROB	E-value
Preeclampsia	0.57 [0.11, 2.88]	-	1 study	27	10	not evaluable	ROB	-
Intrauterine deaths
Adverse outcome	OR 95%CI	I2	k	No. cases	No. exposed	publication bias	ROB	E-value
Perinatal death	2.82 [0.11, 74.36]	-	1 study	1	10	not evaluable	ROB	-
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