metaPreg - Furosemide (versus unexposed) during pregnancy

Furosemide (versus unexposed) updated on 03-11-2025

Table Graphic exposition period:

Adverse outcome	OR 95%CI	I2	k	No. cases	No. exposed	publication bias	ROB	E-value
Congenital malformations
All congenital malformations (majors, minors, majors and minors, or unspecified)	1.60 [0.79, 3.25]	-	1 study	22,865	29	not evaluable	ROB	-
Ano-rectal atresia and stenosis	5.60 [0.33, 93.96]	-	1 study	220	15	not evaluable	ROB	-
Cleft lip with or without cleft palate	1.90 [0.23, 15.95]	-	1 study	1,368	16	not evaluable	ROB	-
Club foot / Talipes equinovarus	2.20 [0.50, 9.74]	-	1 study	2,419	17	not evaluable	ROB	-
Congenital heart defects	1.20 [0.29, 5.04]	-	1 study	4,466	17	not evaluable	ROB	-
Ear malformations	3.51 [0.21, 58.78]	-	1 study	351	15	not evaluable	ROB	-
Hydrocephaly	3.96 [0.24, 66.36]	-	1 study	311	15	not evaluable	ROB	-
Hypospadias	1.80 [0.40, 8.05]	-	1 study	3,032	17	not evaluable	ROB	-
Limb reduction defects (LRD)	4.40 [0.59, 32.88]	-	1 study	545	16	not evaluable	ROB	-
Major congenital malformations	1.60 [0.79, 3.25]	-	1 study	22,865	29	not evaluable	ROB	-
Neural Tube Defects	2.00 [0.28, 14.33]	-	1 study	1,191	16	not evaluable	ROB	-
Oesophageal atresia with or without tracheo-oesophageal fistula	22.80 [5.18, 100.43]	-	1 study	229	17	not evaluable	ROB	45.09 [9.83; .]
Polydactyly	1.70 [0.21, 13.49]	-	1 study	1,730	16	not evaluable	ROB	-
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