metaPreg - Zonisamide (Epilepsy) during pregnancy

Zonisamide (Epilepsy) updated on 04-22-2025

Table Graphic exposition period:

Adverse outcome	OR 95%CI	I2	k	No. cases	No. exposed	publication bias	ROB	E-value
Congenital malformations
All congenital malformations (majors, minors, majors and minors, or unspecified)	1.10 [0.34, 3.58]	0%	5 studies	147	160	not evaluable	ROB	-
Major congenital malformations	1.10 [0.34, 3.58]	0%	5 studies	147	160	not evaluable	ROB	-
Growth parameters and prematurity
Adverse outcome	OR 95%CI	I2	k	No. cases	No. exposed	publication bias	ROB	E-value
Small for gestational age (weight)	1.90 [1.20, 3.00]	-	1 study		125	not evaluable	ROB	3.21 [1.69; .]
2 non statistically significant endpoints reported in only one study
Intrauterine deaths
Adverse outcome	OR 95%CI	I2	k	No. cases	No. exposed	publication bias	ROB	E-value
1 non statistically significant endpoints reported in only one study
Neuro-developmental disorders
Adverse outcome	OR 95%CI	I2	k	No. cases	No. exposed	publication bias	ROB	E-value
1 non statistically significant endpoints reported in only one study