- Medication and Pregnancy KB

Study	Type of data	Exposure measurement	Outcome assessment	Adjustment
Darcie, 2004	prospective cohort	This was a randomized, longitudinal, prospective study comparing 3 groups of patients according to the type of maternal treatment. => Not otherwise specified => Considered as a prospective cohort because no precision indicating that a randomization was carried out.	All newborn were specifically evaluated at birth and then successively in the first 24 hours of birth.	No adjustment. Singleton pregnancy. Exclusion of mothers who had another pathology (such as cardiopathy, hepatopathy, hemopathy, diabetes, or pneumopathy) or had been taking other medications that could interfere with the metabolism of carbohydrates in the newborn.
Wide-Swensson, 1995	randomized controlled trial	The patients were randomized by numbers. The randomization was done in blocks of 6 patients. Information as to which treatment each woman was given was stored in a sealed envelope, which was not opened until the study was completed.	Not specified. Fetal heart rate was recorded by antenatal cardiotocography performed in a quiet room before the antihypertensive treatment was commenced and at every visit.	No adjustment. Randomisation. The women were not to have any drug abuse or ingestion (within 3 months) of medications known to be toxic to major organ systems.