Clomethiazol (Epilepsy = All indications)

Exposed non-exposed studies (cohort)

Study Country
Study period
Population source Exposure definition Non-exposure definition Sample size Rmk

Case-control studies (cohort)

Study Country
Study period
Case Control Sample size Rmk
Bànhidy (Clomethiazol), 2011 Hungary
1980 - 1996
Children affected with congenital abnormalities and who had mothers with medically recorded epilepsy. Newborn infants without congenital abnormality and who had mothers with medically recorded epilepsy. 95 / 90 Congenital abnormalities syndromes caused by major mutant genes or chromosomal aberrations with preconceptional origin were excluded. Exposure period completed with Czeizel 1992.
Czeizel (Clomethiazol), 1992 Hungary
1980 - 1987
Children affected with congenital abnormalities born from treated or untreated mothers. Children without congenital abnormalities born from treated or untreated mothers. 100 / 54 The study design was partly completed thanks to the reference [6] cited in the publication. All congenital abnormalities except spina bifida are overlapped by the publication of Bànhidy 2011. Clomethiazol is a synonym of Chlormethiazol.

master protocol