Study | Country Study period |
Population source | Exposure definition | Non-exposure definition | Sample size | Rmk |
---|
Study | Country Study period |
Case | Control | Sample size | Rmk |
---|---|---|---|---|---|
Bànhidy (Clomethiazol), 2011 |
Hungary 1980 - 1996 |
Children affected with congenital abnormalities and who had mothers with medically recorded epilepsy. | Newborn infants without congenital abnormality and who had mothers with medically recorded epilepsy. | 95 / 90 | Congenital abnormalities syndromes caused by major mutant genes or chromosomal aberrations with preconceptional origin were excluded. Exposure period completed with Czeizel 1992. |
Czeizel (Clomethiazol), 1992 |
Hungary 1980 - 1987 |
Children affected with congenital abnormalities born from treated or untreated mothers. | Children without congenital abnormalities born from treated or untreated mothers. | 100 / 54 | The study design was partly completed thanks to the reference [6] cited in the publication. All congenital abnormalities except spina bifida are overlapped by the publication of Bànhidy 2011. Clomethiazol is a synonym of Chlormethiazol. |