Zotepine - Medication and Pregnancy KB

Zotepine

Exposed non-exposed studies (cohort)

Study	Country Study period	Population source	Exposure definition	Non-exposure definition	Sample size	Rmk
Habermann (Control exposed to FGA), 2013	Germany 1997 - 2009	Subjects were enrolled through the consultation process at Teratology Information Service (TIS Berlin)	Women exposed to Zotepine during pregnancy; comedication with First Generation Antipsycotics (FGA) was allowed. (This is a subgroup of exposure among the whole exposed group considered in the study).	exposed to other treatment, sick Women exposed to First Generation Antipsychotics (FGAs) excluding comedication with Second Generation Antipsychotics (SGA) (cohort I).	2 / 284	Primary analyse on all Atypical Antipsychotics but Raw data are provided for some substances. Cases with potentially embryo- or fetotoxic drugs were not excluded for both the study cohort and the comparison cohort I but were assessed afterward.
Habermann (Control unexposed, disease free), 2013	Germany 1997 - 2009	Subjects were enrolled through the consultation process at Teratology Information Service (TIS Berlin)	Women exposed to Zotepine during pregnancy; comedication with First Generation Antipsycotics (FGA) was allowed. (This is a subgroup of exposure among the whole exposed group considered in the study).	unexposed, disease free Women exposed to teratogenic, fetotoxic, or insufficiently studied agents were excluded as described elsewhere (cohort II).	2 / 1122	Primary analyse on all Atypical Antipsychotics but Raw data are provided for some substances. Cases with potentially embryo- or fetotoxic drugs were not excluded for both the study cohort and the comparison cohort I but were assessed afterward.

Case-control studies (cohort)

Study	Country Study period	Case	Control	Sample size	Rmk

Warning! There are no case-control studies available for this drug.

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