Piracetam (Epilepsy = ALL)

Study	Country Study period	Population source	Exposure definition	Non-exposure definition	Sample size	Rmk
Morrow (Piracetam) (Controls exposed to Lamotrigine, sick), 2006	UK and Ireland 1996 - 2005	Pregnant women with epilepsy, whether or not they were taking an AED, either in monotherapy or polytherapy, and who were referred to the register before the outcome of the pregnancy was known.	Infants of women with epilepsy exposed to piracetam in monotherapy during the first trimester. (This is a subgroup of exposure among the whole exposed group considered in the study).	exposed to other treatment, sick Infants of women with epilepsy exposed to lamotrigine in monotherapy during the first trimester.	1 / 647	Exposure period is completed thanks to Campbell 2014 which is also a UKEPR based study.
Morrow (Piracetam) (Controls unexposed, sick), 2006	UK and Ireland 1996 - 2005	Pregnant women with epilepsy, whether or not they were taking an antiepileptic drug, either in monotherapy or polytherapy, and who were referred to the register before the outcome of the pregnancy was known.	Infants of women with epilepsy exposed to piracetam in monotherapy during the first trimester. (This is a subgroup of exposure among the whole exposed group considered in the study).	unexposed, sick Infants of women with epilepsy and who didn't take any antiepileptic drugs during pregnancy.	1 / 227	Exposure period is completed thanks to Campbell 2014 which is also a UKEPR based study.

Study	Country Study period	Case	Control	Sample size	Rmk