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Reference |
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Bech (Indications other than epilepsy), 2014
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Bech Use of antiepileptic drugs during pregnancy and risk of spontaneous abortion and stillbirth: population based cohort study. BMJ 2014; 349:g5159
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Bech (Mixed indications), 2018
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Bech In utero exposure to antiepileptic drugs is associated with learning disabilities among offspring. J Neurol Neurosurg Psychiatry 2018; 89:1324-1331
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Bjørk (Mixed indications), 2022
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Bjørk Association of Prenatal Exposure to Antiseizure Medication With Risk of Autism and Intellectual Disability. JAMA Neurol 2022; : Daugaard Association of Prenatal Exposure to Valproate and Other Antiepileptic Drugs With Intellectual Disability and Delayed Childhood Milestones. JAMA Netw Open 2020; 3:e2025570
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Blotière (Indications other than epilepsy), 2019
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Blotière Risks of 23 specific malformations associated with prenatal exposure to 10 antiepileptic drugs. Neurology 2019; 93:e167-e180
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Christensen (Indications NOS), 2013
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Christensen Prenatal valproate exposure and risk of autism spectrum disorders and childhood autism. JAMA 2013; 309:1696-703
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Christensen (Indications NOS), 2019
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Christensen Association of Prenatal Exposure to Valproate and Other Antiepileptic Drugs With Risk for Attention-Deficit/Hyperactivity Disorder in Offspring. JAMA Netw Open 2019; 2:e186606
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Christensen (Indications other than epilepsy), 2024
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Christensen Prenatal exposure to antiseizure medications and fetal growth: a population-based cohort study from the Nordic countries. Lancet Reg Health Eur 2024; 38:100849
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Christensen (Mixed indications), 2015
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Christensen Apgar-score in children prenatally exposed to antiepileptic drugs: a population-based cohort study. BMJ Open 2015; 5:e007425
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Coste (Indications other than epilepsy), 2020
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Blotière Risk of early neurodevelopmental outcomes associated with prenatal exposure to the antiepileptic drugs most commonly used during pregnancy: a French nationwide population-based cohort study. BMJ Open 2020; 10:e034829 Coste Risk of early neurodevelopmental disorders associated with in utero exposure to valproate and other antiepileptic drugs: a nationwide cohort study in France. Sci Rep 2020; 10:17362
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Elkjaer (Indications, NOS), 2018
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Elkjaer Association Between Prenatal Valproate Exposure and Performance on Standardized Language and Mathematics Tests in School-aged Children. JAMA Neurol 2018; 75:663-671
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Eros (Indications NOS), 2002
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Eros A population-based case-control teratologic study of nitrazepam, medazepam, tofisopam, alprazolum and clonazepam treatment during pregnancy. Eur J Obstet Gynecol Reprod Biol 2002; 101:147-54
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Källén (Indications NOS), 2013
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Källén The use of central nervous system active drugs during pregnancy. Pharmaceuticals (Basel) 2013; 6:1221-86
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Kilic (Mixed indications), 2014
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Kilic Birth outcomes after prenatal exposure to antiepileptic drugs--a population-based study. Epilepsia 2014; 55:1714-21
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Noh (Mixed indications), 2022
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Noh First-trimester exposure to benzodiazepines and risk of congenital malformations in offspring: A population-based cohort study in South Korea. PLoS Med 2022; 19:e1003945
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Oberlander (Controls unexposed, disease free) (Indications other than epilepsy), 2004
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Misri Relation between prenatal maternal mood and anxiety and neonatal health. Can J Psychiatry 2004; 49:684-9 Oberlander Pharmacologic factors associated with transient neonatal symptoms following prenatal psychotropic medication exposure. J Clin Psychiatry 2004; 65:230-7 Reebye Affect Expression and Self-Regulation Capacities of Infants Exposed in utero to Psychotropics. Front Psychiatry 2012; 3:11 Reebye, P.N. Affect expression in prenatally psychotropic exposed and nonexposed mother-infant dyads Infant Ment. Health J. 2002; 23:403-.
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Oberlander (Controls unexposed, sick) (Indications other than epilepsy), 2004
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Oberlander Pharmacologic factors associated with transient neonatal symptoms following prenatal psychotropic medication exposure. J Clin Psychiatry 2004; 65:230-7 Reebye Affect Expression and Self-Regulation Capacities of Infants Exposed in utero to Psychotropics. Front Psychiatry 2012; 3:11 Reebye, P.N. Affect expression in prenatally psychotropic exposed and nonexposed mother-infant dyads Infant Ment. Health J. 2002; 23:403-.
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Sheehy (Indications NOS), 2019
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Berard, A. Individual benzodiazepine exposure during early pregnancy and the risk of spontaneous abortion Eur. Psychiatry 2019; 56:S118-. Sheehy Association Between Incident Exposure to Benzodiazepines in Early Pregnancy and Risk of Spontaneous Abortion. JAMA Psychiatry 2019; 76:948-957 Sheehy, O. Incident exposure to benzodiazepine in early pregnancy and the risk of spontaneous abortion Birth Defects Res. 2019; 111:507-. Zhao, J.-P. Individual benzodiazepine exposure during early pregnancy and the risk of spontaneous abortion Birth Defects Res. 2018; 110:774-.
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The NAAED (Indications NOS), 2023
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Hernández-Díaz Comparative safety of antiepileptic drugs during pregnancy. Neurology 2012;78:1692-9 Holmes Risk of malformations for specific AED in monotherapy and the control groups (Annual Update Latest Study Data - Consulted in February 2025) https://www.aedpregnancyregistry.org/
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Tinker (Mixed indications), 2019
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Tinker Use of benzodiazepine medications during pregnancy and potential risk for birth defects, National Birth Defects Prevention Study, 1997-2011. Birth Defects Res 2019; 111:613-620
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Veiby (Mixed indications), 2014
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Veiby Fetal growth restriction and birth defects with newer and older antiepileptic drugs during pregnancy. J. Neurol. 2014; 261:579-88
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