Labetalol (versus unexposed)

Study Reference
Bateman, 2016

Bateman Late Pregnancy Beta Blocker Exposure and Risks of Neonatal Hypoglycemia and Bradycardia. Pediatrics 2016; 138:

Bergman, 2018

Bergman Beta-Blocker Use in Pregnancy and Risk of Specific Congenital Anomalies: A European Case-Malformed Control Study. Drug Saf 2018; 41:415-427

Caton, 2009

Caton Antihypertensive medication use during pregnancy and the risk of cardiovascular malformations. Hypertension 2009; 54:63-70

Chan, 2010

Chan WS Neurocognitive development of children following in-utero exposure to labetalol for maternal hypertension: a cohort study using a prospectively collected database. Hypertens Pregnancy 2010;29:271-83

Cruickshank, 1990

Cruickshank Atenolol in essential hypertension during pregnancy. BMJ 1990; 301:1103

Cruickshank, 1991

Cruickshank Maternal Obstetric Outcome Measures in A Randomised Controlled Study of Labetalol in the Treatment of Hypertension in Pregnancy, Clinical and Experimental Hypertension. Part B: Hypertension in Pregnancy, 1991, 10:3, 333-344.

Delteil, 2024

Delteil Beta-blockers and pregnancy - An EFEMERIS study Scientific report. 2024: 1-67.

Duan, 2018

Duan Beta-blocker subtypes and risk of low birth weight in newborns. J Clin Hypertens (Greenwich) 2018; 20:1603-1609

Fisher, 2017
Fitton (Controls unexposed, disease free), 2020

Fitton In Utero Antihypertensive Medication Exposure and Neonatal Outcomes: A Data Linkage Cohort Study. Hypertension 2020; 75:628-633

Fitton (Controls unexposed, sick), 2020

Fitton In Utero Antihypertensive Medication Exposure and Neonatal Outcomes: A Data Linkage Cohort Study. Hypertension 2020; 75:628-633

Petersen, 2012

Petersen Beta-Blocker treatment during pregnancy and adverse pregnancy outcomes: a nationwide population-based cohort study. BMJ Open 2012; 2:

Sibai, 1990

Sibai A comparison of no medication versus methyldopa or labetalol in chronic hypertension during pregnancy. Am J Obstet Gynecol 1990; 162:960-6; discussion 966-7

Thewissen (Controls unexposed, disease free), 2017

Thewissen Neonatal haemodynamic effects following foetal exposure to labetalol in hypertensive disorders of pregnancy. J Matern Fetal Neonatal Med 2017; 30:1533-1538

Thewissen (Controls unexposed, sick), 2017

Thewissen Neonatal haemodynamic effects following foetal exposure to labetalol in hypertensive disorders of pregnancy. J Matern Fetal Neonatal Med 2017; 30:1533-1538

Van Zutphen, 2014

Van Zutphen AR Maternal hypertension, medication use, and hypospadias in the National Birth Defects Prevention Study. Obstet Gynecol 2014;123:309-17

Xiang, 2020

Xiang Treatment of pregnancy-induced hypertension compared with labetalol, low dose aspirin and placebo. Cell Mol Biol (Noisy-le-grand) 2020; 66:9-13