TNF-alpha inhibitors

Study Reference
Agosti, 2015

Agosti M Long-Term Follow-Up of Children Born to Mothers with Chronic Arthritides and Exposed in Utero to Anti-TNF-Alpha Agents: A Case-Control Study Ann Rheum Dis 2015;74(Suppl 2):709–710

Broms (Controls exposed to other treatments), 2020

Broms Anti-TNF treatment during pregnancy and birth outcomes: A population-based study from Denmark, Finland, and Sweden. Pharmacoepidemiol Drug Saf 2020; 29:316-327

Broms (Controls unexposed, disease free), 2020

Broms Anti-TNF treatment during pregnancy and birth outcomes: A population-based study from Denmark, Finland, and Sweden. Pharmacoepidemiol Drug Saf 2020; 29:316-327

Bröms a (Controls unexposed, disease free), 2016

Bröms G Low Risk of Birth Defects for Infants Whose Mothers Are Treated With Anti-Tumor Necrosis Factor Agents During Pregnancy Clin Gastroenterol Hepatol. 2016a;14(2):234-241

Bröms a (Controls unexposed, sick), 2016

Bröms G Low Risk of Birth Defects for Infants Whose Mothers Are Treated With Anti-Tumor Necrosis Factor Agents During Pregnancy Clin Gastroenterol Hepatol. 2016a;14(2):234-241

Bröms b, 2016

Broms G Preterm birth in women with inflammatory bowel disease - the association with disease activity and drug treatment. Scand J Gastroenterol 2016;51:1462-1469

Carman - Etanercept (Controls unexposed, disease free), 2017

Carman WJ Pregnancy and infant outcomes including major congenital malformations among women with chronic inflammatory arthritis or psoriasis, with and without etanercept use. Pharmacoepidemiol Drug Saf 2017;26:1109-1118

Carman - Etanercept (Controls unexposed, sick), 2017

Carman WJ Pregnancy and infant outcomes including major congenital malformations among women with chronic inflammatory arthritis or psoriasis, with and without etanercept use. Pharmacoepidemiol Drug Saf 2017;26:1109-1118

Casanova, 2013

Casanova MJ Safety of thiopurines and anti-TNF-? drugs during pregnancy in patients with inflammatory bowel disease. Am J Gastroenterol 2013;108:433-40

Chambers - Adalimumab (Controls unexposed, disease free), 2017

Chambers CD Birth Outcomes Following Pregnancy Exposure to Adalimumab: The OTIS Autoimmune Diseases in Pregnancy Project Pharmacoepidemiology and Drug Safety 2017;26:218–219

Chambers - Adalimumab (Controls unexposed, sick, ADA only), 2017

Chambers CD Birth Outcomes Following Pregnancy Exposure to Adalimumab: The OTIS Autoimmune Diseases in Pregnancy Project Pharmacoepidemiology and Drug Safety 2017;26:218–219

Chambers - Etanercept, 2015

Chambers Pregnancy Outcome in Women Treated with Etanercept: An Update on the OTIS Autoimmune Diseases in Pregnancy Project Pharmacoepidemiology and Drug Safety 2015; 24:402–402

Chaparro, 2018

Chaparro M Long-Term Safety of In Utero Exposure to Anti-TNF? Drugs for the Treatment of Inflammatory Bowel Disease: Results from the Multicenter European TEDDY Study. Am J Gastroenterol 2018;113:396-403

Cooper, 2014

Cooper Brief report: Risk of adverse fetal outcomes associated with immunosuppressive medications for chronic immune-mediated diseases in pregnancy. 2014; 66:444-50

De Lima, 2018

de Lima A Hepatitis B Vaccination Effective in Children Exposed to Anti-Tumour Necrosis Factor Alpha in Utero. J Crohns Colitis 2018;12:948-953

De Lima (Controls unexposed, disease free), 2016

de Lima A Tailored anti-TNF therapy during pregnancy in patients with IBD: maternal and fetal safety. Gut 2016;65:1261-8

De Lima (Treatment stopped during pregnancy, sick), 2016

de Lima A Tailored anti-TNF therapy during pregnancy in patients with IBD: maternal and fetal safety. Gut 2016;65:1261-8

De Lorenzo (Controls unexposed, disease free), 2020

De Lorenzo Neonatal outcomes of children born to mothers on biological agents during pregnancy: State of the art and perspectives. Pharmacol. Res. 2020; 152:104583

De Lorenzo (Controls unexposed, sick), 2020

De Lorenzo Neonatal outcomes of children born to mothers on biological agents during pregnancy: State of the art and perspectives. Pharmacol. Res. 2020; 152:104583

Desai, 2017

Desai RJ Risk of serious infections associated with use of immunosuppressive agents in pregnant women with autoimmune inflammatory conditions: cohort study. BMJ 2017;356:j895

Diav-Citrin (Controls exposed to other treatments), 2014

Diav-Citrin O Pregnancy outcome following gestational exposure to TNF-alpha-inhibitors: a prospective, comparative, observational study. Reprod Toxicol 2014;43:78-84

Diav-Citrin (Controls unexposed, disease free), 2014

Diav-Citrin O Pregnancy outcome following gestational exposure to TNF-alpha-inhibitors: a prospective, comparative, observational study. Reprod Toxicol 2014;43:78-84

Drechsel, 2020

Drechsel Pregnancy outcomes in DMARD-exposed patients with juvenile idiopathic arthritis-results from a JIA biologic registry. Rheumatology (Oxford) 2020; 59:603-612

Duricova, 2019

Duricova Safety of Anti-TNF-Alpha Therapy During Pregnancy on Long-term Outcome of Exposed Children: A Controlled, Multicenter Observation. Inflamm. Bowel Dis. 2019; 25:789-796

Fu - Etanercept, 2019

Fu A randomized controlled trial of etanercept in the treatment of refractory recurrent spontaneous abortion with innate immune disorders. Taiwan J Obstet Gynecol 2019; 58:621-625

Hoxha, 2017

Hoxha A Pregnancy and foetal outcomes following anti-tumor necrosis factor alpha therapy: A prospective multicentre study. Joint Bone Spine 2017;84:169-173

Komoto, 2016

Komoto Pregnancy outcome in women with inflammatory bowel disease treated with anti-tumor necrosis factor and/or thiopurine therapy: a multicenter study from Japan. Intest Res 2016; 14:139-45

Langen, 2014

Langen High rate of preterm birth in pregnancies complicated by rheumatoid arthritis. Am J Perinatol 2014; 31:9-14

Lichtenstein - infliximab, 2018

Lichtenstein GR Pregnancy Outcomes Reported During the 13-Year TREAT Registry: A Descriptive Report. Am J Gastroenterol 2018;113:1678-1688

Luu, 2018

Luu M Continuous Anti-TNF? Use Throughout Pregnancy: Possible Complications For the Mother But Not for the Fetus. A Retrospective Cohort on the French National Health Insurance Database (EVASION). Am J Gastroenterol 2018;113:1669-1677

Moens (Controls exposed to Vedolizumab), 2020

Moens Pregnancy outcomes in inflammatory bowel disease patients treated with vedolizumab, anti-TNF or conventional therapy: results of the European CONCEIVE study. Aliment. Pharmacol. Ther. 2020; 51:129-138

Moens (Controls unexposed, sick), 2020

Moens Pregnancy outcomes in inflammatory bowel disease patients treated with vedolizumab, anti-TNF or conventional therapy: results of the European CONCEIVE study. Aliment. Pharmacol. Ther. 2020; 51:129-138

Schnitzler (Controls unexposed, disease free), 2011

Schnitzler F Outcome of pregnancy in women with inflammatory bowel disease treated with antitumor necrosis factor therapy. Inflamm Bowel Dis 2011;17:1846-54

Schnitzler (Unexposed control, sick), 2011

Schnitzler F Outcome of pregnancy in women with inflammatory bowel disease treated with antitumor necrosis factor therapy. Inflamm Bowel Dis 2011;17:1846-54

Seirafi, 2014

Seirafi M Factors associated with pregnancy outcome in anti-TNF treated women with inflammatory bowel disease. Aliment Pharmacol Ther 2014;40:363-73

Verstappen, 2011

Verstappen SM Anti-TNF therapies and pregnancy: outcome of 130 pregnancies in the British Society for Rheumatology Biologics Register. Ann Rheum Dis 2011;70:823-6

Viktil (Controls exposed to other treatments), 2012

Viktil Outcomes after anti-rheumatic drug use before and during pregnancy: a cohort study among 150,000 pregnant women and expectant fathers. Scand J Rheumatol 2012; 41:196-201

Viktil (Controls unexposed, NOS), 2012

Viktil Outcomes after anti-rheumatic drug use before and during pregnancy: a cohort study among 150,000 pregnant women and expectant fathers. Scand J Rheumatol 2012; 41:196-201

Vinet, 2013

Vinet E Induced abortions in women with rheumatoid arthritis receiving methotrexate. Arthritis Care Res (Hoboken) 2013;65:1365-9

Vinet (Controls unexposed, disease free), 2018

Vinet E Serious Infections in Rheumatoid Arthritis Offspring Exposed to Tumor Necrosis Factor Inhibitors: A Cohort Study. Arthritis Rheumatol 2018;70:1565-1571

Vinet (Controls unexposed, sick), 2018

Vinet E Serious Infections in Rheumatoid Arthritis Offspring Exposed to Tumor Necrosis Factor Inhibitors: A Cohort Study. Arthritis Rheumatol 2018;70:1565-1571

Weber-Schoendorfer, 2015

Weber-Schoendorfer C Pregnancy outcome after TNF-? inhibitor therapy during the first trimester: a prospective multicentre cohort study. Br J Clin Pharmacol 2015;80:727-39

Zbinden (rheumatoid arthritis), 2018

Zbinden Risk for adverse pregnancy outcome in axial spondyloarthritis and rheumatoid arthritis: disease activity matters. Rheumatology (Oxford) 2018; 57:1235-1242

Zbinden b (axial spondyloarthritis), 2018

Zbinden Risk for adverse pregnancy outcome in axial spondyloarthritis and rheumatoid arthritis: disease activity matters. Rheumatology (Oxford) 2018; 57:1235-1242