Study |
Reference |
Alsfouk, 2021
|
Alsfouk, B.A. Antiseizure medications use during pregnancy and congenital malformations: A retrospective study in Saudi Arabia Saudi Pharm. J. 2021; 29:939-.
|
AlSheikh, 2020
|
AlSheikh Prevalence of epilepsy in Saudi pregnant women and possible effects of anti-epileptic drugs on pregnancy outcomes. Neurosciences (Riyadh) 2020; 25:32-37
|
Artama (Controls unexposed, disease free), 2013
|
Artama Effects of maternal epilepsy and antiepileptic drug use during pregnancy on perinatal health in offspring: nationwide, retrospective cohort study in Finland. Drug Saf 2013; 36:359-69
|
Artama (Controls unexposed, sick), 2013
|
Artama Effects of maternal epilepsy and antiepileptic drug use during pregnancy on perinatal health in offspring: nationwide, retrospective cohort study in Finland. Drug Saf 2013; 36:359-69
|
Aydin, 2020
|
Aydin Retrospective evaluation of pregnancy outcomes with maternal epilepsy. Journal of Clinical Obstetrics and Gynecology 2020; 30:20-
|
Baker (Controls unexposed, disease free), 2015
|
Baker IQ at 6 years after in utero exposure to antiepileptic drugs: a controlled cohort study. Neurology 2015; 84:382-90 Bromley The prevalence of neurodevelopmental disorders in children prenatally exposed to antiepileptic drugs. J Neurol Neurosurg Psychiatry 2013; 84:637-43
|
Baker (Controls unexposed, sick), 2015
|
Baker IQ at 6 years after in utero exposure to antiepileptic drugs: a controlled cohort study. Neurology 2015; 84:382-90 Bromley The prevalence of neurodevelopmental disorders in children prenatally exposed to antiepileptic drugs. J Neurol Neurosurg Psychiatry 2013; 84:637-43
|
Bjørk (Controls unexposed, disease free), 2018
|
Bjørk Association of Folic Acid Supplementation During Pregnancy With the Risk of Autistic Traits in Children Exposed to Antiepileptic Drugs In Utero. JAMA Neurol 2018; 75:160-168
|
Bjørk (Controls unexposed, NOS), 2022
|
Bjørk Association of Prenatal Exposure to Antiseizure Medication With Risk of Autism and Intellectual Disability. JAMA Neurol 2022; :
|
Bjørk (Controls unexposed, sick), 2022
|
Bjørk Association of Prenatal Exposure to Antiseizure Medication With Risk of Autism and Intellectual Disability. JAMA Neurol 2022; :
|
Bjørk (Controls unexposed, sick), 2018
|
Bjørk Association of Folic Acid Supplementation During Pregnancy With the Risk of Autistic Traits in Children Exposed to Antiepileptic Drugs In Utero. JAMA Neurol 2018; 75:160-168
|
Borthen (Controls unexposed, disease free), 2011
|
Borthen Delivery outcome of women with epilepsy: a population-based cohort study. BJOG 2010; 117:1537-43 Borthen Obstetric outcome in women with epilepsy: a hospital-based, retrospective study. BJOG 2011; 118:956-65 Veiby Fetal growth restriction and birth defects with newer and older antiepileptic drugs during pregnancy. J Neurol 2014; 261:579-88
|
Borthen (Controls unexposed, disease free), 2010
|
Borthen Delivery outcome of women with epilepsy: a population-based cohort study. BJOG 2010; 117:1537-43
|
Borthen (Controls unexposed, sick), 2010
|
Borthen Delivery outcome of women with epilepsy: a population-based cohort study. BJOG 2010; 117:1537-43
|
Borthen (Controls unexposed, sick), 2011
|
Borthen Delivery outcome of women with epilepsy: a population-based cohort study. BJOG 2010; 117:1537-43 Borthen Obstetric outcome in women with epilepsy: a hospital-based, retrospective study. BJOG 2011; 118:956-65 Veiby Fetal growth restriction and birth defects with newer and older antiepileptic drugs during pregnancy. J Neurol 2014; 261:579-88
|
Bromley (Controls unexposed, disease free), 2010
|
Baker IQ at 6 years after in utero exposure to antiepileptic drugs: a controlled cohort study. Neurology 2015; 84:382-90 Bromley Early cognitive development in children born to women with epilepsy: a prospective report. Epilepsia 2010; 51:2058-65 Bromley The prevalence of neurodevelopmental disorders in children prenatally exposed to antiepileptic drugs. J Neurol Neurosurg Psychiatry 2013; 84:637-43
|
Bromley (Controls unexposed, disease free), 2013
|
Bromley Autism spectrum disorders following in utero exposure to antiepileptic drugs. Neurology 2008; 71:1923-4 Bromley The prevalence of neurodevelopmental disorders in children prenatally exposed to antiepileptic drugs. J Neurol Neurosurg Psychiatry 2013; 84:637-43
|
Bromley (Controls unexposed, sick), 2010
|
Baker IQ at 6 years after in utero exposure to antiepileptic drugs: a controlled cohort study. Neurology 2015; 84:382-90 Bromley Early cognitive development in children born to women with epilepsy: a prospective report. Epilepsia 2010; 51:2058-65 Bromley The prevalence of neurodevelopmental disorders in children prenatally exposed to antiepileptic drugs. J Neurol Neurosurg Psychiatry 2013; 84:637-43
|
Bromley (Controls unexposed, sick), 2013
|
Bromley Autism spectrum disorders following in utero exposure to antiepileptic drugs. Neurology 2008; 71:1923-4 Bromley The prevalence of neurodevelopmental disorders in children prenatally exposed to antiepileptic drugs. J Neurol Neurosurg Psychiatry 2013; 84:637-43
|
Bromley (Lamotrigine) (Epilepsy), 2023
|
Bromley Neurodevelopment of babies born to mothers with epilepsy: A prospective observational cohort study. Epilepsia 2023; 64:2454-2471
|
Campbell, 2014
|
Campbell E Malformation risks of antiepileptic drug monotherapies in pregnancy: updated results from the UK and Ireland Epilepsy and Pregnancy Registers. J Neurol Neurosurg Psychiatry 2014;85:1029-34 Morrow Malformation risks of antiepileptic drugs in pregnancy: a prospective study from the UK Epilepsy and Pregnancy Register. J Neurol Neurosurg Psychiatry 2006; 77:193-8
|
Cassina, 2013
|
Cassina Pregnancy outcome in women exposed to antiepileptic drugs: teratogenic role of maternal epilepsy and its pharmacologic treatment. Reprod Toxicol 2013; 39:50-7
|
Charlton, 2011
|
Charlton Comparing the General Practice Research Database and the UK Epilepsy and Pregnancy Register as tools for postmarketing teratogen surveillance: anticonvulsants and the risk of major congenital malformations. Drug Saf 2011; 34:157-71 Morrow Malformation risks of antiepileptic drugs in pregnancy: a prospective study from the UK Epilepsy and Pregnancy Register. J Neurol Neurosurg Psychiatry 2006; 77:193-8
|
Charlton (Controls unexposed, disease free), 2017
|
Bromley The prevalence of neurodevelopmental disorders in children prenatally exposed to antiepileptic drugs. J Neurol Neurosurg Psychiatry 2013; 84:637-43 Charlton Sensitivity of the UK Clinical Practice Research Datalink to Detect Neurodevelopmental Effects of Medicine Exposure in Utero: Comparative Analysis of an Antiepileptic Drug-Exposed Cohort. Drug Saf 2017; 40:387-397
|
Charlton (Controls unexposed, sick), 2017
|
Bromley The prevalence of neurodevelopmental disorders in children prenatally exposed to antiepileptic drugs. J Neurol Neurosurg Psychiatry 2013; 84:637-43 Charlton Sensitivity of the UK Clinical Practice Research Datalink to Detect Neurodevelopmental Effects of Medicine Exposure in Utero: Comparative Analysis of an Antiepileptic Drug-Exposed Cohort. Drug Saf 2017; 40:387-397
|
Cohen, 2019
|
Cohen Anticonvulsant Mood Stabilizer and Lithium Use and Risk of Adverse Pregnancy Outcomes. J Clin Psychiatry 2019; 80:
|
Cohen-Israel, 2018
|
Cohen-Israel Short- and long-term complications of in utero exposure to lamotrigine. Br J Clin Pharmacol 2018; 84:189-194
|
Cummings, 2011
|
Cummings Neurodevelopment of children exposed in utero to lamotrigine, sodium valproate and carbamazepine. Arch Dis Child 2011; 96:643-7
|
Dean, 2007
|
Dean Fetal anticonvulsant syndromes and polymorphisms in MTHFR, MTR, and MTRR. Am J Med Genet A 2007; 143A:2303-11
|
Diav-Citrin, 2017
|
Diav-Citrin Is it safe to use lamotrigine during pregnancy? A prospective comparative observational study. Birth Defects Res 2017; 109:1196-1203 Rihtman Developmental outcomes at preschool age after fetal exposure to valproic acid and lamotrigine: cognitive, motor, sensory and behavioral function. Reprod Toxicol 2013; 41:115-25
|
Dreier, 2021
|
Dreier, J. Prenatal exposure to antiseizure medication and intrauterine growth restriction in offspring of women with epilepsy. Epilepsia 2021; 62:6-.
|
Dreier, 2023
|
Dreier Prenatal Exposure to Antiseizure Medication and Incidence of Childhood- and Adolescence-Onset Psychiatric Disorders. JAMA Neurol 2023; 80:568-577
|
Gopinath, 2015
|
Gopinath Children (10-12 years age) of women with epilepsy have lower intelligence, attention and memory: Observations from a prospective cohort case control study. Epilepsy Res 2015; 117:58-62
|
He, 2017
|
He Pregnancy outcome in women with epilepsy in Western China: A prospective hospital based study. Epilepsy Behav 2017; 74:10-14
|
Holmes, 2008
|
Holmes Increased frequency of isolated cleft palate in infants exposed to lamotrigine during pregnancy. Neurology 2008; 70:2152-8
|
Hosny, 2021
|
Hosny Risk factors of fetal deaths and major birth defects in newborns of women with epilepsy: An Egyptian prospective study. Epilepsy Behav 2021; 123:108251
|
Husebye (Controls unexposed, disease free), 2020
|
Husebye Language impairment in children aged 5 and 8 years after antiepileptic drug exposure in utero - the Norwegian Mother and Child Cohort Study. Eur J Neurol 2020; 27:667-675
|
Husebye (Controls unexposed, sick), 2020
|
Husebye Language impairment in children aged 5 and 8 years after antiepileptic drug exposure in utero - the Norwegian Mother and Child Cohort Study. Eur J Neurol 2020; 27:667-675
|
Kasradze, 2017
|
Kasradze Cognitive functions in children exposed to antiepileptic drugs in utero - Study in Georgia. Epilepsy Behav 2017; 66:105-112
|
Kini, 2006
|
Kini Dysmorphic features: an important clue to the diagnosis and severity of fetal anticonvulsant syndromes. Arch Dis Child Fetal Neonatal Ed 2006; 91:F90-5
|
Li, 2023
|
He Pregnancy outcome in women with epilepsy in Western China: A prospective hospital based study. Epilepsy Behav 2017; 74:10-14 Li Pregnancy characteristics and adverse outcomes in offspring of women with epilepsy: a prospective registry study from Mainland China. Front Neurol 2023; 14:1195003
|
Mawer (Controls unexposed, disease free), 2010
|
Kini Influence of the MTHFR genotype on the rate of malformations following exposure to antiepileptic drugs in utero. Eur J Med Genet ; 50:411-20 Mawer Pregnancy with epilepsy: obstetric and neonatal outcome of a controlled study. Seizure 2010; 19:112-9
|
Mawer (Controls unexposed, sick), 2010
|
Kini Influence of the MTHFR genotype on the rate of malformations following exposure to antiepileptic drugs in utero. Eur J Med Genet ; 50:411-20 Mawer Pregnancy with epilepsy: obstetric and neonatal outcome of a controlled study. Seizure 2010; 19:112-9
|
Meador, 2023
|
Meador Two-Year-Old Cognitive Outcomes in Children of Pregnant Women With Epilepsy in the Maternal Outcomes and Neurodevelopmental Effects of Antiepileptic Drugs Study. JAMA Neurol 2021; 78:927-936 Meador Cognitive outcomes at age 3 years in children with fetal exposure to antiseizure medications (MONEAD study) in the USA: a prospective, observational cohort study. Lancet Neurol 2023; 22:712-722
|
Meador (Controls unexposed, disease free), 2020
|
Meador Fetal loss and malformations in the MONEAD study of pregnant women with epilepsy. Neurology 2020; 94:e1502-e1511
|
Meador (Controls unexposed, sick), 2020
|
Meador Fetal loss and malformations in the MONEAD study of pregnant women with epilepsy. Neurology 2020; 94:e1502-e1511
|
Miškov (Controls unexposed, disease free), 2016
|
Miskov Croatian Pregnant Women with Epilepsy and Effects of Antiepileptic Drugs Exposure in their Offspring - seven years of prospective surveillance. American Epilepsy Society; Texas 2010
|
Miškov (Controls unexposed, sick), 2016
|
Miskov Croatian Pregnant Women with Epilepsy and Effects of Antiepileptic Drugs Exposure in their Offspring - seven years of prospective surveillance. American Epilepsy Society; Texas 2010
|
Pekoz (Lamotrigine) (Epilepsy), 2023
|
Pekoz Birth outcomes in pregnant women with epilepsy: A Nationwide multicenter study from Turkiye. Epilepsia 2023; 64:2310-2321
|
Petersen (Controls unexposed NOS), 2017
|
Petersen Antiepileptic drugs prescribed in pregnancy and prevalence of major congenital malformations: comparative prevalence studies. Clin Epidemiol 2017; 9:95-103
|
Petersen (Controls unexposed, sick), 2017
|
Petersen Antiepileptic drugs prescribed in pregnancy and prevalence of major congenital malformations: comparative prevalence studies. Clin Epidemiol 2017; 9:95-103
|
Razaz (Controls unexposed, disease free), 2017
|
Razaz Association Between Pregnancy and Perinatal Outcomes Among Women With Epilepsy. JAMA Neurol 2017; 74:983-991
|
Razaz (Controls unexposed, sick), 2017
|
Razaz Association Between Pregnancy and Perinatal Outcomes Among Women With Epilepsy. JAMA Neurol 2017; 74:983-991
|
Ren (Lamotrigine) (Epilepsy), 2023
|
Elkjaer Association Between Prenatal Valproate Exposure and Performance on Standardized Language and Mathematics Tests in School-aged Children. JAMA Neurol 2018; 75:663-671 Ren Prenatal Carbamazepine Exposure and Academic Performance in Adolescents: A Population-Based Cohort Study. Neurology 2023; 100:e728-e738
|
Rihtman, 2013
|
Rihtman Developmental outcomes at preschool age after fetal exposure to valproic acid and lamotrigine: cognitive, motor, sensory and behavioral function. Reprod Toxicol 2013; 41:115-25
|
Thomas (Controls unexposed, disease free), 2021
|
Thomas Malformation risk of antiepileptic drug exposure during pregnancy in women with epilepsy: Results from a pregnancy registry in South India. Epilepsia 2017; 58:274-281
|
Thomas (Controls unexposed, sick), 2021
|
Thomas Malformation risk of antiepileptic drug exposure during pregnancy in women with epilepsy: Results from a pregnancy registry in South India. Epilepsia 2017; 58:274-281 Thomas Malformation risk of new anti-epileptic drugs in women with epilepsy; observational data from the Kerala registry of epilepsy and pregnancy (KREP). Seizure 2021; 93:127-132
|
Trivedi, 2018
|
Trivedi Spontaneous fetal loss in women with epilepsy: prospective data from pregnancy registry in India. Epilepsy Res 2018; 146:50-53
|
Vajda, 2018
|
Vajda Anti-epileptic drug exposure and risk of foetal death in utero. Acta Neurol Scand 2018; 137:20-23
|
Vajda, 2019
|
Vajda Is lamotrigine a significant human teratogen? Observations from the Australian Pregnancy Register. Seizure 2010; 19:558-61 Vajda Teratogenicity of the newer antiepileptic drugs--the Australian experience. J Clin Neurosci 2012; 19:57-9 Vajda The prescribing of antiepileptic drugs for pregnant Australian women. Aust N Z J Obstet Gynaecol 2012; 52:49-53 Vajda Associations between particular types of fetal malformation and antiepileptic drug exposure in utero. Acta Neurol Scand 2013; 128:228-34 Vajda The teratogenic risk of antiepileptic drug polytherapy. Epilepsia 2010; 51:805-10 Vajda The Australian Register of Antiepileptic Drugs in Pregnancy: the first 1002 pregnancies. Aust N Z J Obstet Gynaecol 2007; 47:468-74 Vajda Changing Australian prescribing patterns for antiepileptic drugs in pregnancy and their possible consequences. J Clin Neurosci 2007; 14:611-7 Vajda Australian pregnancy registry of women taking antiepileptic drugs. Epilepsia 2004; 45:1466 Vajda Antiepileptic drugs and foetal malformation: analysis of 20 years of data in a pregnancy register. Seizure 2019; 65:6-11 Vajda The teratogenicity of the newer antiepileptic drugs - an update. Acta Neurol Scand 2014; 130:234-8
|
Vajda, 2013
|
Vajda Associations between particular types of fetal malformation and antiepileptic drug exposure in utero. Acta Neurol Scand 2013; 128:228-34 Vajda Antiepileptic drugs and foetal malformation: analysis of 20 years of data in a pregnancy register. Seizure 2019; 65:6-11
|
Van Marter (Controls unexposed, disease free), 2021
|
Van Marter, L.J. Neonatal Outcomes in the MONEAD Study of Pregnant Women with Epilepsy Journal of Pediatrics: X 2021; 7:514-.
|
Van Marter (Controls unexposed, sick), 2021
|
Van Marter, L.J. Neonatal Outcomes in the MONEAD Study of Pregnant Women with Epilepsy Journal of Pediatrics: X 2021; 7:514-.
|
Vanya (Controls unexposed, sick), 2015
|
Vanya EFFECTS OF MATERNAL EPILEPSY AND ANTIEPILEPTIC THERAPY IN WOMEN DURING PREGNANCY. Ideggyogy Sz 2015; 68:105-12
|
Veiby (Controls unexposed, disease free), 2014
|
Veiby Fetal growth restriction and birth defects with newer and older antiepileptic drugs during pregnancy. J Neurol 2014; 261:579-88
|
Veiby (Controls unexposed, disease free) a, 2013
|
Bjørk Association of Folic Acid Supplementation During Pregnancy With the Risk of Autistic Traits in Children Exposed to Antiepileptic Drugs In Utero. JAMA Neurol 2018; 75:160-168 Veiby Exposure to antiepileptic drugs in utero and child development: a prospective population-based study. Epilepsia 2013; 54:1462-72 Veiby Early child development and exposure to antiepileptic drugs prenatally and through breastfeeding: a prospective cohort study on children of women with epilepsy. JAMA Neurol 2013; 70:1367-74
|
Veiby (Controls unexposed, disease free) b, 2013
|
Bjørk Association of Folic Acid Supplementation During Pregnancy With the Risk of Autistic Traits in Children Exposed to Antiepileptic Drugs In Utero. JAMA Neurol 2018; 75:160-168 Farmen Intrauterine growth retardation in foetuses of women with epilepsy. Seizure 2015; 28:76-80 Veiby Fetal growth restriction and birth defects with newer and older antiepileptic drugs during pregnancy. J Neurol 2014; 261:579-88 Veiby Exposure to antiepileptic drugs in utero and child development: a prospective population-based study. Epilepsia 2013; 54:1462-72
|
Veiby (Controls unexposed, sick), 2014
|
Veiby Fetal growth restriction and birth defects with newer and older antiepileptic drugs during pregnancy. J Neurol 2014; 261:579-88
|
Veiby (Controls unexposed, sick) a, 2013
|
Bjørk Association of Folic Acid Supplementation During Pregnancy With the Risk of Autistic Traits in Children Exposed to Antiepileptic Drugs In Utero. JAMA Neurol 2018; 75:160-168 Veiby Exposure to antiepileptic drugs in utero and child development: a prospective population-based study. Epilepsia 2013; 54:1462-72 Veiby Early child development and exposure to antiepileptic drugs prenatally and through breastfeeding: a prospective cohort study on children of women with epilepsy. JAMA Neurol 2013; 70:1367-74
|
Veiby (Controls unexposed, sick) b, 2013
|
Bjørk Association of Folic Acid Supplementation During Pregnancy With the Risk of Autistic Traits in Children Exposed to Antiepileptic Drugs In Utero. JAMA Neurol 2018; 75:160-168 Farmen Intrauterine growth retardation in foetuses of women with epilepsy. Seizure 2015; 28:76-80 Veiby Fetal growth restriction and birth defects with newer and older antiepileptic drugs during pregnancy. J Neurol 2014; 261:579-88 Veiby Exposure to antiepileptic drugs in utero and child development: a prospective population-based study. Epilepsia 2013; 54:1462-72
|
Videman, 2016
|
Videman Evidence for spared attention to faces in 7-month-old infants after prenatal exposure to antiepileptic drugs. Epilepsy Behav 2016; 64:62-68
|
Wiggs, 2020
|
Wiggs Antiseizure medication use during pregnancy and risk of ASD and ADHD in children. Neurology 2020; 95:e3232-e3240
|