Primidone (All indications)

Study Reference
Bànhidy (Primidone), 2011

Bànhidy Efficacy of medical care of epileptic pregnant women based on the rate of congenital abnormalities in their offspring. Congenit Anom (Kyoto) 2011; 51:34-42

Battino (Primidone), 1999

Battino Intrauterine growth in the offspring of epileptic women: a prospective multicenter study. Epilepsy Res 1999; 36:53-60

Battino (Primidone), 1992

Battino Malformations in offspring of 305 epileptic women: a prospective study. Acta Neurol Scand 1992; 85:204-7

Canger Malformations in offspring of women with epilepsy: a prospective study. Epilepsia 1999; 40:1231-6

Burja (Primidone) (Controls unexposed, disease free), 2006

Burja The frequency of neonatal morbidity after exposure to antiepileptic drugs in utero: a retrospective population-based study. Wien Klin Wochenschr 2006; 118 Suppl 2:12-6

Burja (Primidone) (Controls unexposed, sick), 2006

Burja The frequency of neonatal morbidity after exposure to antiepileptic drugs in utero: a retrospective population-based study. Wien Klin Wochenschr 2006; 118 Suppl 2:12-6

Canger (Primidone), 1999

Canger Malformations in offspring of women with epilepsy: a prospective study. Epilepsia 1999; 40:1231-6

Czeizel (Primidone), 1992

Bànhidy Efficacy of medical care of epileptic pregnant women based on the rate of congenital abnormalities in their offspring. Congenit Anom (Kyoto) 2011; 51:34-42

Czeizel Evaluation of anticonvulsant drugs during pregnancy in a population-based Hungarian study. Eur J Epidemiol 1992; 8:122-7

Dean (Primidone), 2002

Dean Long term health and neurodevelopment in children exposed to antiepileptic drugs before birth. J Med Genet 2002; 39:251-9

Kaaja (Primidone), 2003

Kaaja Major malformations in offspring of women with epilepsy. Neurology 2003; 60:575-9

Källén (Primidone) (Controls exposed to Lamotrigine, sick) (Indications NOS), 2013

Källén The use of central nervous system active drugs during pregnancy. Pharmaceuticals (Basel) 2013; 6:1221-86

Wide Major malformations in infants exposed to antiepileptic drugs in utero, with emphasis on carbamazepine and valproic acid: a nation-wide, population-based register study. Acta Paediatr 2004; 93:174-6

Källén (Primidone) (Controls unexposed, NOS) (Indications NOS), 2013

Källén The use of central nervous system active drugs during pregnancy. Pharmaceuticals (Basel) 2013; 6:1221-86

Kaneko (Primidone), 1999

Battino Malformations in offspring of 305 epileptic women: a prospective study. Acta Neurol Scand 1992; 85:204-7

Canger Malformations in offspring of women with epilepsy: a prospective study. Epilepsia 1999; 40:1231-6

Kaneko Congenital malformations due to antiepileptic drugs. Epilepsy Res 1999; 33:145-58

Kaneko Teratogenicity of antiepileptic drugs: analysis of possible risk factors. Epilepsia ; 29:459-67

Katz (Primidone), 2001

Katz Current Management of Epilepsy and Pregnancy: Fetal Outcome, Congenital Malformations, and Developmental Delay. Epilepsy Behav 2001; 2:119-123

Kilic (Primidone) (Controls exposed to Lamotrigine, sick) (Mixed indications), 2014

Kilic Birth outcomes after prenatal exposure to antiepileptic drugs--a population-based study. Epilepsia 2014; 55:1714-21

Kilic (Primidone) (Controls unexposed NOS) (Mixed indications), 2014

Kilic Birth outcomes after prenatal exposure to antiepileptic drugs--a population-based study. Epilepsia 2014; 55:1714-21

Kilic (Primidone) (Controls unexposed, sick) (Mixed indications), 2014

Kilic Birth outcomes after prenatal exposure to antiepileptic drugs--a population-based study. Epilepsia 2014; 55:1714-21

Kini (Primidone) (Controls exposed to Lamotrigine, sick), 2006

Kini Dysmorphic features: an important clue to the diagnosis and severity of fetal anticonvulsant syndromes. Arch Dis Child Fetal Neonatal Ed 2006; 91:F90-5

Kini (Primidone) (Controls unexposed, sick), 2006

Kini Dysmorphic features: an important clue to the diagnosis and severity of fetal anticonvulsant syndromes. Arch Dis Child Fetal Neonatal Ed 2006; 91:F90-5

Koch (Primidone), 1996

Koch Antiepileptic drug treatment in pregnancy: drug side effects in the neonate and neurological outcome. Acta Paediatr 1996; 85:739-46

Lowe (Primidone) (Controls unexposed, disease free), 1973

Lowe Congenital malformations among infants born to epileptic women. Lancet 1973; 1:9-10

Lowe (Primidone) (Controls unexposed, sick), 1973

Lowe Congenital malformations among infants born to epileptic women. Lancet 1973; 1:9-10

Samrén (Primidone), 1999

Samrén Antiepileptic drug regimens and major congenital abnormalities in the offspring. Ann Neurol 1999; 46:739-46

Steegers-Theunissen (Primidone), 1994

Steegers-Theunissen Factors influencing the risk of abnormal pregnancy outcome in epileptic women: a multi-centre prospective study. Epilepsy Res 1994; 18:261-9

Titze (Primidone) (Controls unexposed, disease free), 2008

Titze Prenatal and family risks of children born to mothers with epilepsy: effects on cognitive development. Dev Med Child Neurol 2008; 50:117-22

Titze (Primidone) (Controls unexposed, sick), 2008

Titze Prenatal and family risks of children born to mothers with epilepsy: effects on cognitive development. Dev Med Child Neurol 2008; 50:117-22

Tomson (Primidone), 2018

Tomson Comparative risk of major congenital malformations with eight different antiepileptic drugs: a prospective cohort study of the EURAP registry. Lancet Neurol 2018; 17:530-538

Tomson Dose-dependent risk of malformations with antiepileptic drugs: an analysis of data from the EURAP epilepsy and pregnancy registry. Lancet Neurol 2011; 10:609-17

Vajda (Primidone) (Controls exposed to Lamotrigine, sick), 2019

Vajda Associations between particular types of fetal malformation and antiepileptic drug exposure in utero. Acta Neurol Scand 2013; 128:228-34

Vajda Antiepileptic drugs and foetal malformation: analysis of 20 years of data in a pregnancy register. Seizure 2019; 65:6-11

Vajda The teratogenicity of the newer antiepileptic drugs - an update. Acta Neurol Scand 2014; 130:234-8

Vajda (Primidone) (Controls unexposed, sick), 2019

Vajda Associations between particular types of fetal malformation and antiepileptic drug exposure in utero. Acta Neurol Scand 2013; 128:228-34

Vajda Antiepileptic drugs and foetal malformation: analysis of 20 years of data in a pregnancy register. Seizure 2019; 65:6-11

Vajda The teratogenicity of the newer antiepileptic drugs - an update. Acta Neurol Scand 2014; 130:234-8