Almotriptan - Medication and Pregnancy KB

Almotriptan

Exposed non-exposed, cohort studies

Study	Country Study period Study design	Data source	Exposure definition	Non-exposure definition	Exposition period	Sample size (exposed/unexposed) Or (case / control)	Remarks	Risk of bias
Källén (control exposed to ergots) 2011	Sweden 1995 - 2008 population based cohort propective	The Swedish Medical Birth Register	Infants born to women who had used Almotriptan during pregnancy. (This is a subgroup of exposure among the whole exposed group considered in the study).	exposed to other treatment, sick Infants born to women who had used Ergots drugs for migraine during pregnancy. (This is a subgroup of exposure among the whole exposed group considered in the study).	1st trimester	6 / 527	Exposed groups of the whole study: drugs for migraine (ergots or triptans).
Källén (control exposed to ergots) 2011	Sweden 1995 - 2008 population based cohort propective	The Swedish Medical Birth Register	Pregnant women who attend antenatal clinics in Sweden (which the vast majority do) are interviewed by a midwife and asked about drugs used since the pregnancy started. This interview is usually made before the end of the first trimester (usually between weeks 10 and 12 of pregnancy).		1st trimester	6 / 527
Källén (control unexposed, disease free) 2011	Sweden 1995 - 2008 population based cohort propective	The Swedish Medical Birth Register	Infants born to women who had used drugs for migraine (triptans or ergots) during pregnancy. Exposure to Almotriptan provided and considered as a separate subgroup.	unexposed, disease free Infants born to women who did not use drugs for migraine.	1st trimester	6 / 1229901	Exposed groups of the whole study: drugs for migraine (ergots or triptans). 1229901= Total number of infants (n=1233228) - Number of infants whose mother used drugs for migraine in 1st trimester (n=3327)
Källén (control unexposed, disease free) 2011	Sweden 1995 - 2008 population based cohort propective	The Swedish Medical Birth Register	Pregnant women who attend antenatal clinics in Sweden (which the vast majority do) are interviewed by a midwife and asked about drugs used since the pregnancy started. This interview is usually made before the end of the first trimester (usually between weeks 10 and 12 of pregnancy).		1st trimester	6 / 1229901

Case-control studies

Study	Country Study period Study design	Data source	Case	Control	Exposition	Exposition period	Sample size (exposed/unexposed) Or (case / control)	Remarks	Risk of bias

Risk of bias: : NA; : low; : moderate; : serious; : critical; : unclear;

Empty. There are no case-control studies available for this drug.

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