Almotriptan

Study	Country Study period	Population source	Exposure definition	Non-exposure definition	Sample size	Rmk
Källén (control exposed to ergots), 2011	Sweden 1995 - 2008	All deliveries in Sweden (1 211 670 women) recorded in the Medical Birth Register with data from antenatal care.	Infants born to women who had used Almotriptan during pregnancy. (This is a subgroup of exposure among the whole exposed group considered in the study).	exposed to other treatment, sick Infants born to women who had used Ergots drugs for migraine during pregnancy. (This is a subgroup of exposure among the whole exposed group considered in the study).	6 / 527	Exposed groups of the whole study: drugs for migraine (ergots or triptans).
Källén (control unexposed, disease free), 2011	Sweden 1995 - 2008	All deliveries in Sweden (1 211 670 women) recorded in the Medical Birth Register with data from antenatal care.	Infants born to women who had used drugs for migraine (triptans or ergots) during pregnancy. Exposure to Almotriptan provided and considered as a separate subgroup.	unexposed, disease free Infants born to women who did not use drugs for migraine.	6 / 1229901	Exposed groups of the whole study: drugs for migraine (ergots or triptans). 1229901= Total number of infants (n=1233228) - Number of infants whose mother used drugs for migraine in 1st trimester (n=3327)

Study	Country Study period	Case	Control	Sample size	Rmk