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Clomethiazol (Epilepsy = All indications)
Overall results
Study description
Excluded studies
Table
Graphic
auto
during pregnancy (anytime or not specified)
1st trimester
2nd trimester
3rd trimester
2nd and/or 3rd trimester
throughout pregnancy
early pregnancy
days before delivery
late pregnancy
preconception-only
periconceptional
preconceptional for kinetic reason
at least 1st trimester
3 months (or more) before pregnancy or during pregnancy
1st and 2nd trimester
3 months or more before pregnancy or1st trimester
Whatever the period exposition
individual studies
Outcome
TE
95% CI
n cases
n exposed
k
Pub. bias
Congenital malformations
All congenital malformations (majors, minors, majors and minors, or unspecified)
Bànhidy (Clomethiazol), 2011
1
2.74
[
0.10
; 74.88]
14
2
not evaluable
Congenital heart defects
Bànhidy (Clomethiazol), 2011
1
2.33
[
0.04
; 136.99]
6
1
not evaluable
Hypospadias
0
-
-
-
-
-
Major congenital malformations
Bànhidy (Clomethiazol), 2011
1
2.74
[
0.10
; 74.88]
14
2
not evaluable
Neural Tube Defects
0
-
-
-
-
-
Polydactyly
0
-
-
-
-
-
Spina bifida
0
-
-
-
-
-
0.0
100.0
1.0