Lansoprazole

Table   Graphic  
individual studies
OutcomeTE95% CIn casesn exposedkPub. bias Congenital malformations All congenital malformations (majors, minors, majors and minors, or unspecified) Diav-Citrin, 2005 Pasternak, 2010 Matok, 2012 Choi a, 2023 41.01[0.90; 1.14]114,8267,475not evaluable Major congenital malformations Diav-Citrin, 2005 Pasternak, 2010 Matok, 2012 Choi a, 2023 41.01[0.90; 1.14]114,8267,475not evaluable Hypospadias Källèn, 1998 Lind, 2013 Choi a, 2023 31.57[0.70; 3.51]3,3423,309not evaluable Atrial septal defect Källèn, 1998 149.70[1.92; 1288.78]113not evaluable Cleft palate Choi a, 2023 11.00[0.45; 2.25]2,2876,404not evaluable Congenital heart defects Choi a, 2023 10.96[0.80; 1.16]42,2696,404not evaluable Congenital hydronephrosis Källèn, 1998 15.05[0.20; 130.52]113not evaluable Down syndrom / Trisomy 21 Källèn, 1998 115.24[0.29; 800.69]-13not evaluable Encephalocele Källèn, 1998 15.05[0.20; 130.52]113not evaluable Hydrocephaly Choi a, 2023 10.94[0.23; 3.81]7866,404not evaluable Patent ductus arterious Källèn, 1998 115.24[0.29; 800.69]-13not evaluable Ventricular septal defect Källèn, 1998 115.24[0.29; 800.69]-13not evaluable Growth parameters and prematurity Low birth weight (< 2500g) Choi b, 2023 10.91[0.83; 1.00]104,5388,678not evaluable Preterm (< 37 weeks) Diav-Citrin, 2005 11.30[0.57; 2.99]9348not evaluable Long term consequences Infant asthma Yitshak-Sade, 2016 11.70[1.38; 2.09]-346not evaluable Intrauterine deaths Early intrauterine death (< 22 weeks) Diav-Citrin, 2005 11.50[0.62; 3.62]6462not evaluable Ectopic pregnancy 0----- Elective/induced termination of pregnancy Diav-Citrin, 2005 13.96[1.65; 9.51]3462not evaluable Late intrauterine deaths (> 22 weeks) Diav-Citrin, 2005 12.81[0.13; 59.28]262not evaluable Neuro-developmental disorders Neuro-developmental disorders (as a whole) Fejzo, 2015 12.00[0.87; 4.60]13825not evaluable0.0100.01.0

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