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Nifedipine (versus unexposed)
Overall results
Study description
Excluded studies
Table
Graphic
auto
during pregnancy (anytime or not specified)
1st trimester
2nd trimester
3rd trimester
2nd and/or 3rd trimester
throughout pregnancy
early pregnancy
days before delivery
late pregnancy
preconception-only
periconceptional
preconceptional for kinetic reason
at least 1st trimester
3 months (or more) before pregnancy or during pregnancy
1st and 2nd trimester
3 months or more before pregnancy or1st trimester
Whatever the period exposition
individual studies
Outcome
TE
95% CI
n cases
n exposed
k
Pub. bias
Congenital malformations
All congenital malformations (majors, minors, majors and minors, or unspecified)
Weber-Schoendorfer, 2008
1
1.31
[
0.39
; 4.42]
36
51
not evaluable
Limb defects
Weber-Schoendorfer, 2008
1
2.04
[
0.10
; 39.95]
3
51
not evaluable
Major congenital malformations
Weber-Schoendorfer, 2008
1
2.07
[
0.46
; 9.35]
16
51
not evaluable
Oesophageal atresia with or without tracheo-oesophageal fistula
Vermes, 2015
1
3.27
[
0.98
; 10.93]
221
9
not evaluable
Growth parameters and prematurity
Preterm (< 37 weeks)
Weber-Schoendorfer, 2008
1
7.18
[
3.74
; 13.80]
64
51
not evaluable
Intrauterine deaths
Early intrauterine death (< 22 weeks)
Weber-Schoendorfer, 2008
1
2.48
[
1.23
; 4.99]
70
65
not evaluable
Late intrauterine deaths (> 22 weeks)
Weber-Schoendorfer, 2008
1
6.21
[
1.52
; 25.43]
9
65
not evaluable
Elective/induced termination of pregnancy
Weber-Schoendorfer, 2008
1
4.38
[
2.10
; 9.14]
41
76
not evaluable
0.0
50.0
1.0
