Metoprolol (versus unexposed)

Table   Graphic  
individual studies
OutcomeTE95% CIn casesn exposedkPub. bias Congenital malformations All congenital malformations (majors, minors, majors and minors, or unspecified) Delteil, 2024 13.71[1.33; 10.34]4,05847not evaluable Cleft palate Puho, 2007 12.10[0.79; 5.61]601124not evaluable Hypospadias Van Zutphen, 2014 11.82[0.33; 10.05]2,1316not evaluable Major congenital malformations Delteil, 2024 13.71[1.33; 10.34]4,05847not evaluable Growth parameters and prematurity Small for gestational age (weight) Tanaka, 2016 Duan, 2018 Albertini, 2023 31.74[0.96; 3.14]32,530352not evaluable Low birth weight (< 2500g) Duan, 2018 Vaclavik, 2024 22.57[2.35; 2.80]19,436870not evaluable Preterm (< 37 weeks) Vaclavik, 2024 12.07[1.88; 2.27]-490not evaluable Very low birth weight (< 1500g) Duan, 2018 13.43[1.83; 6.45]3,451324not evaluable Maternal consequences Caesarean Duan, 2018 Vaclavik, 2024 22.26[1.77; 2.89]104,3421,975not evaluable Assisted deliveries (forceps, vacuum, ...) Duan, 2018 11.27[0.65; 2.47]8,242324not evaluable Preeclampsia Duan, 2018 12.00[0.74; 5.36]2,334324not evaluable Neonatal disorders Low Apgar score (< 7) (at 1 min) Duan, 2018 11.33[0.84; 2.11]16,774324not evaluable Low Apgar score (< 7) (at 10 min) Duan, 2018 12.44[0.78; 7.61]1,433324not evaluable Low Apgar score (< 7) (at 5 min) Duan, 2018 13.11[1.54; 6.28]3,032324not evaluable Low Apgar score (< 7) (NOS) Vaclavik, 2024 11.59[1.46; 1.74]-593not evaluable Neonatal bradycardia Bateman, 2016 10.59[0.32; 1.09]731,484not evaluable Neonatal hypoglycemia Bateman, 2016 11.64[1.15; 2.33]1401,484not evaluable0.220.01.0

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