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Pindolol (versus unexposed)
Overall results
Study description
Excluded studies
Table
Graphic
auto
during pregnancy (anytime or not specified)
1st trimester
2nd trimester
3rd trimester
2nd and/or 3rd trimester
throughout pregnancy
early pregnancy
days before delivery
late pregnancy
preconception-only
periconceptional
preconceptional for kinetic reason
at least 1st trimester
3 months (or more) before pregnancy or during pregnancy
1st and 2nd trimester
3 months or more before pregnancy or1st trimester
Whatever the period exposition
individual studies
Outcome
TE
95% CI
n cases
n exposed
k
Pub. bias
Congenital malformations
All congenital malformations (majors, minors, majors and minors, or unspecified)
0
-
-
-
-
-
Major congenital malformations
0
-
-
-
-
-
Minor congenital malformations
0
-
-
-
-
-
Neural Tube Defects
Medveczky, 2004
1
5.80
[
1.29
; 26.14]
1,202
12
not evaluable
Growth parameters and prematurity
Low birth weight (< 2500g)
Rosenfeld, 1986
1
0.93
[
0.28
; 3.06]
18
23
not evaluable
Preterm (< 37 weeks)
Rosenfeld, 1986
1
1.20
[
0.31
; 4.69]
11
23
not evaluable
Small for gestational age (weight)
Rosenfeld, 1986
1
2.11
[
0.34
; 12.86]
6
23
not evaluable
Maternal consequences
Caesarean
Rosenfeld, 1986
1
1.35
[
0.41
; 4.46]
18
23
not evaluable
Neonatal disorders
Low Apgar score (< 7) (NOS)
Rosenfeld, 1986
1
0.60
[
0.09
; 4.01]
5
23
not evaluable
Neonatal hypoglycemia
Rosenfeld, 1986
1
0.45
[
0.04
; 5.40]
3
23
not evaluable
Intrauterine deaths
Perinatal death
Rosenfeld, 1986
1
0.96
[
0.02
; 50.34]
-
23
not evaluable
0.0
100.0
1.0