metaPreg - Verapamil (versus unexposed) during pregnancy

Verapamil (versus unexposed)

Table Graphic exposition period:

Adverse outcome	OR 95%CI	I2	k	No. cases	No. exposed	publication bias	ROB	E-value
Congenital malformations
All congenital malformations (majors, minors, majors and minors, or unspecified)	2.51 [1.01, 6.28]	-	1 study	39	56	not evaluable	ROB	4.46 [1.08; .]
Limb defects	1.89 [0.10, 36.98]	-	1 study	3	55	not evaluable	ROB	-
Major congenital malformations	1.91 [0.42, 8.63]	-	1 study	16	55	not evaluable	ROB	-
Neural Tube Defects	1.87 [0.11, 32.37]	-	1 study	1,202	8	not evaluable	ROB	-
Growth parameters and prematurity
Adverse outcome	OR 95%CI	I2	k	No. cases	No. exposed	publication bias	ROB	E-value
Preterm (< 37 weeks)	2.69 [1.34, 5.44]	60%	2 studies	59	70	not evaluable	ROB	4.83 [2.00; .]
Low birth weight (< 2500g)	2.61 [1.58, 4.31]	-	1 study		18	not evaluable	ROB	4.66 [2.54; .]
Maternal consequences
Adverse outcome	OR 95%CI	I2	k	No. cases	No. exposed	publication bias	ROB	E-value
Caesarean	1.76 [1.21, 2.55]	-	1 study		43	not evaluable	ROB	2.92 [1.72; .]
Neonatal disorders
Adverse outcome	OR 95%CI	I2	k	No. cases	No. exposed	publication bias	ROB	E-value
Low Apgar score (< 7) (NOS)	1.58 [0.97, 2.58]	-	1 study		19	not evaluable	ROB	-
Intrauterine deaths
Adverse outcome	OR 95%CI	I2	k	No. cases	No. exposed	publication bias	ROB	E-value
Early intrauterine death (< 22 weeks)	0.90 [0.32, 2.57]	-	1 study	63	58	not evaluable	ROB	-
Elective/induced termination of pregnancy	1.78 [0.61, 5.24]	-	1 study	34	62	not evaluable	ROB	-
Late intrauterine deaths (> 22 weeks)	2.25 [0.27, 19.02]	-	1 study	7	58	not evaluable	ROB	-
Hide endpoints reported in only one study ...