Verapamil (versus unexposed)

Table   Graphic     exposition period:

Congenital malformations
Adverse outcome OR 95%CII2k No. casesNo. exposedpublication biasROBE-value
All congenital malformations (majors, minors, majors and minors, or unspecified)2.51 [1.01, 6.28]-1 study3956not evaluable ROB4.46 [1.08; .]
Limb defects1.89 [0.10, 36.98]-1 study355not evaluable ROB-
Major congenital malformations1.91 [0.42, 8.63]-1 study1655not evaluable ROB-
Neural Tube Defects1.87 [0.11, 32.37]-1 study1,2028not evaluable ROB-

Growth parameters and prematurity
Adverse outcome OR 95%CII2k No. casesNo. exposedpublication biasROBE-value
Preterm (< 37 weeks)4.01 [1.98, 8.11]-1 study5955not evaluable ROB7.48 [3.37; .]

Intrauterine deaths
Adverse outcome OR 95%CII2k No. casesNo. exposedpublication biasROBE-value
Early intrauterine death (< 22 weeks)0.90 [0.32, 2.57]-1 study6358not evaluable ROB-
Elective/induced termination of pregnancy1.78 [0.61, 5.24]-1 study3462not evaluable ROB-
Late intrauterine deaths (> 22 weeks)2.25 [0.27, 19.02]-1 study758not evaluable ROB-

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