Lacosamide (All indications) updated on 12-01-2025

Table   Graphic     exposition period:

Congenital malformations
Adverse outcome OR 95%CII2k No. casesNo. exposedpublication biasROBE-value
All congenital malformations (majors, minors, majors and minors, or unspecified)1.53 [0.41, 5.71]0%5 studies161146serious ROB-
Major congenital malformations1.53 [0.41, 5.71]0%5 studies161146serious ROB-

Growth parameters and prematurity
Adverse outcome OR 95%CII2k No. casesNo. exposedpublication biasROBE-value
Preterm (< 37 weeks)0.51 [0.23, 1.13]-1 study19688not evaluable ROB-
Small for gestational age (weight)0.96 [0.45, 2.03]-1 study13288not evaluable ROB-

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