metaPreg - Temazepam during pregnancy

Temazepam updated on 02-10-2025

Table Graphic exposition period:

Adverse outcome	OR 95%CI	I2	k	No. cases	No. exposed	publication bias	ROB	E-value
Congenital malformations
Congenital heart defects	1.96 [1.02, 3.79]	0%	2 studies	2,687	379	not evaluable	ROB	3.33 [1.14; .]
Abdominal wall defects	12.69 [1.42, 113.82]	-	1 study	5	379	not evaluable	ROB	24.87 [2.18; .]
Cleft lip with or without cleft palate	-	-	0 study					-
Cleft palate	-	-	0 study					-
12 non statistically significant endpoints reported in only one study
Intrauterine deaths
Adverse outcome	OR 95%CI	I2	k	No. cases	No. exposed	publication bias	ROB	E-value
Early intrauterine deaths (< 22 weeks) / Spontaneous abortions	2.74 [1.29, 5.83]	-	1 study	27,149	29	not evaluable	ROB	4.92 [1.90; .]