Clorazepate

Study	Country Study period	Population source	Exposure definition	Non-exposure definition	Sample size	Rmk

Study	Country Study period	Case	Control	Sample size	Rmk
Bonnot, 2003	France 1976 - 1997	Infants with the studied congenital malformation.	Infants with a malformations other than this one studied.	-9 / -9	Total number of infants with a congenital malformation is 13703, but the number of cases changes according to the studied malformations. Raw data not sufficient to calculate OR (data for 'control' groups not available).
Kitchin, 2022	Spain 2002 - 2015	Pregnant woman suffering a miscarriage.	Pregnant woman randomly selected from the whole cohort among women who were still at risk within follow-up, by risk-set sampling and individually matched to cases.	18070 / 54209	Authors provided 2 exposure definitions: Use in both periods (continuers) and Use only during pregnancy (new users) => use of data for 'Use in both periods (continuers)', to decrease misclassification bais (exposure occurred before outcome).