Nitrazepam (Epilepsy)

Study	Country Study period	Population source	Exposure definition	Non-exposure definition	Sample size	Rmk
Thomas (Epilepsy) (Controls exposed to LTG), 2022	India 1998 - 2019	All babies of women with epilepsy (WWE) enrolled in the pre-pregnancy stage or in the first trimester of pregnancy, who were over 12 months of age on 31st December, 2020 (and less than 24 months).	Infants of women with epilepsy who were exposed to Nitrazepam monotherapy at anytime during the antenatal period.	exposed to other treatment, sick Infants of women with epilepsy who were exposed to Lamotrigine monotherapy at anytime during the antenatal period.	2 / 26	No use of delayed mental development, because discrepancy in LTG data '1/26 (11.5%)'.
Thomas (Epilepsy) (Controls unexposed, sick), 2022	India 1998 - 2019	All babies of women with epilepsy (WWE) enrolled in the pre-pregnancy stage or in the first trimester of pregnancy, who were over 12 months of age on 31st December, 2020 (and less than 24 months).	Infants of women with epilepsy who were exposed to Nitrazepam monotherapy at anytime during the antenatal period.	unexposed, sick Infants of women with epilepsy who were not exposed to any antiseizure medications (ASMs) during pregnancy.	2 / 110

Study	Country Study period	Case	Control	Sample size	Rmk