Tenofovir (all routes except local)

Study Reference
Bagkeris, 2015

Bagkeris Pregnancy outcomes in HIV-positive women in Ukraine, 2000-12 (European Collaborative Study in EuroCoord): an observational cohort study. Lancet HIV 2015; 2:e385-92

Bérard (Controls exposed to other ARV), 2017

Bérard Antiretroviral combination use during pregnancy and the risk of major congenital malformations. AIDS 2017; 31:2267-2277

Bérard (Controls unexposed, disease free), 2017

Bérard Antiretroviral combination use during pregnancy and the risk of major congenital malformations. AIDS 2017; 31:2267-2277

Bérard (Controls unexposed, sick), 2017

Bérard Antiretroviral combination use during pregnancy and the risk of major congenital malformations. AIDS 2017; 31:2267-2277

Brogly, 2010

Brogly Birth defects among children born to human immunodeficiency virus-infected women: pediatric AIDS clinical trials protocols 219 and 219C. Pediatr. Infect. Dis. J. 2010; 29:721-7

Calitri, 2014

Calitri The second generation of HIV-1 vertically exposed infants: a case series from the Italian Register for paediatric HIV infection. BMC Infect. Dis. 2014; 14:277

Caniglia, 2018

Caniglia Emulating a target trial of antiretroviral therapy regimens started before conception and risk of adverse birth outcomes. AIDS 2018; 32:113-120

Celen, 2013

Celen Efficacy and safety of tenofovir disoproxil fumarate in pregnancy for the prevention of vertical transmission of HBV infection. World J. Gastroenterol. 2013; 19:9377-82

Chang, 2019

Chang Decreased neonatal hepatitis B virus (HBV) viremia by maternal tenofovir treatment predicts reduced chronic HBV infection in children born to highly viremic mothers. Aliment. Pharmacol. Ther. 2019; 50:306-316

Chen, 2015

Chen Efficacy of maternal tenofovir disoproxil fumarate in interrupting mother-to-infant transmission of hepatitis B virus. Hepatology 2015; 62:375-86

Chetty, 2018

Chetty Preterm delivery and small-for-gestation outcomes in HIV-infected pregnant women on antiretroviral therapy in rural South Africa: Results from a cohort study, 2010-2015. PLoS ONE 2018; 13:e0192805

Chi, 2007

Chi Single-dose tenofovir and emtricitabine for reduction of viral resistance to non-nucleoside reverse transcriptase inhibitor drugs in women given intrapartum nevirapine for perinatal HIV prevention: an open-label randomised trial. Lancet 2007; 370:1698-705

Colbers, 2015

Colbers Atazanavir exposure is effective during pregnancy regardless of tenofovir use. Antivir. Ther. (Lond.) 2015; 20:57-64

Crain, 2011

Crain Point-of-care capillary blood lactate measurements in human immunodeficiency virus-uninfected children with in utero exposure to human immunodeficiency virus and antiretroviral medications. Pediatr. Infect. Dis. J. 2011; 30:1069-74

Dadabhai, 2019

Dadabhai Pregnancy Outcomes in the Era of Universal Antiretroviral Treatment in Sub-Saharan Africa (POISE Study). J. Acquir. Immune Defic. Syndr. 2019; 80:7-14

Ejigu, 2019

Ejigu Pregnancy outcome among HIV-infected women on different antiretroviral therapies in Ethiopia: a cohort study. BMJ Open 2019; 9:e027344

Favarato, 2019

Favarato Stillbirth in Women Living With HIV Delivering in the United Kingdom and Ireland: 2007-2015. J. Acquir. Immune Defic. Syndr. 2019; 82:9-16

Floridia, 2013

Floridia Birth defects in a national cohort of pregnant women with HIV infection in Italy, 2001-2011. BJOG 2013; 120:1466-75

Floridia, 2018

Floridia Brief Report: Abacavir/Lamivudine and Tenofovir/Emtricitabine in Pregnant Women With HIV: Laboratory and Clinical Outcomes in an Observational National Study. J. Acquir. Immune Defic. Syndr. 2018; 78:99-104

Fowler, 2016

Fowler Benefits and Risks of Antiretroviral Therapy for Perinatal HIV Prevention. N. Engl. J. Med. 2016; 375:1726-1737

Garcia-Otero, 2016

Garcia-Otero Zidovudine treatment in HIV-infected pregnant women is associated with fetal cardiac remodelling. AIDS 2016; 30:1393-401

Gibb, 2012

Gibb Pregnancy and infant outcomes among HIV-infected women taking long-term ART with and without tenofovir in the DART trial. PLoS Med. 2012; 9:e1001217

Greenup (Controls exposed to lamivudine), 2014

Greenup Efficacy and safety of tenofovir disoproxil fumarate in pregnancy to prevent perinatal transmission of hepatitis B virus. J. Hepatol. 2014; 61:502-7

Greenup (Controls unexposed, sick), 2014

Greenup Efficacy and safety of tenofovir disoproxil fumarate in pregnancy to prevent perinatal transmission of hepatitis B virus. J. Hepatol. 2014; 61:502-7

Heffron, 2018

Heffron Pregnancy outcomes and infant growth among babies with in-utero exposure to tenofovir-based preexposure prophylaxis for HIV prevention. AIDS 2018; 32:1707-1713

Jourdain a, 2018

Jourdain Tenofovir versus Placebo to Prevent Perinatal Transmission of Hepatitis B. N. Engl. J. Med. 2018; 378:911-923

Knapp, 2012

Knapp Prevalence of congenital anomalies in infants with in utero exposure to antiretrovirals. Pediatr. Infect. Dis. J. 2012; 31:164-70

Kolgelier, 2016

Kolgelier Monitoring and treatment results of 88 HBsAg-positive pregnant women. Clin Exp Obstet Gynecol 2016; 43:866-870

Lin, 2018

Lin Efficacy of tenofovir in preventing perinatal transmission of HBV infection in pregnant women with high viral loads. Sci Rep 2018; 8:15514

Liu (Controls exposed to LDT), 2019

Liu Efficacy and safety of telbivudine and tenofovir disoproxil fumarate in preventing hepatitis B vertical transmission: A real-life practice. J. Viral Hepat. 2019; 26:1170-1177

Liu (Controls unexposed, sick), 2019

Liu Efficacy and safety of telbivudine and tenofovir disoproxil fumarate in preventing hepatitis B vertical transmission: A real-life practice. J. Viral Hepat. 2019; 26:1170-1177

Malaba, 2017

Malaba Antiretroviral therapy use during pregnancy and adverse birth outcomes in South African women. Int J Epidemiol 2017; 46:1678-1689

Mehta, 2019

Mehta Birth outcomes following antiretroviral exposure during pregnancy: Initial results from a pregnancy exposure registry in South Africa. South Afr J HIV Med 2019; 20:971

Moodley (Controls exposed to other treatments), 2016

Moodley Improved pregnancy outcomes with increasing antiretroviral coverage in South Africa. BMC Pregnancy Childbirth 2016; 16:35

Moodley (Controls unexposed, sick), 2016

Moodley Improved pregnancy outcomes with increasing antiretroviral coverage in South Africa. BMC Pregnancy Childbirth 2016; 16:35

Mugo, 2014

Mugo Pregnancy incidence and outcomes among women receiving preexposure prophylaxis for HIV prevention: a randomized clinical trial. JAMA 2014; 312:362-71

Pan, 2016

Pan Tenofovir to Prevent Hepatitis B Transmission in Mothers with High Viral Load. N. Engl. J. Med. 2016; 374:2324-34

Phiri, 2014

Phiri First trimester exposure to antiretroviral therapy and risk of birth defects. Pediatr. Infect. Dis. J. 2014; 33:741-6

Pintye, 2017

Pintye Maternal Tenofovir Disoproxil Fumarate Use During Pregnancy Is Not Associated With Adverse Perinatal Outcomes Among HIV-infected East African Women: A Prospective Study. J. Infect. Dis. 2017; 216:1561-1568

Pintye, 2015

Pintye Maternal Tenofovir Disoproxil Fumarate Use in Pregnancy and Growth Outcomes among HIV-Exposed Uninfected Infants in Kenya. Infect Dis Obstet Gynecol 2015; 2015:276851

Prieto (Controls exposed to other ARVs), 2014

Prieto Birth defects in a cohort of infants born to HIV-infected women in Spain, 2000-2009. BMC Infect. Dis. 2014; 14:700

Prieto (Controls unexposed, sick), 2014

Prieto Birth defects in a cohort of infants born to HIV-infected women in Spain, 2000-2009. BMC Infect. Dis. 2014; 14:700

Ransom, 2013

Ransom Infant growth outcomes after maternal tenofovir disoproxil fumarate use during pregnancy. J. Acquir. Immune Defic. Syndr. 2013; 64:374-81

Rice, 2018

Rice Risk for Speech and Language Impairments in Preschool Age HIV-exposed Uninfected Children With In Utero Combination Antiretroviral Exposure. Pediatr. Infect. Dis. J. 2018; 37:678-685

Rice, 2013

Rice Evaluation of risk for late language emergence after in utero antiretroviral drug exposure in HIV-exposed uninfected infants. Pediatr. Infect. Dis. J. 2013; 32:e406-13

Rough, 2018

Rough Birth Outcomes for Pregnant Women with HIV Using Tenofovir-Emtricitabine. N. Engl. J. Med. 2018; 378:1593-1603

Samadi Kochaksaraei, 2016

Samadi Kochaksaraei Clinical course of 161 untreated and tenofovir-treated chronic hepatitis B pregnant patients in a low hepatitis B virus endemic region. J. Viral Hepat. 2016; 23:15-22

Seidel, 2020

Seidel Safety of tenofovir during pregnancy: early growth outcomes and hematologic side effects in HIV-exposed uninfected infants. Eur. J. Pediatr. 2020; 179:99-109

Seo, 2018

Seo Effect of antiviral therapy in reducing perinatal transmission of hepatitis B virus and maternal outcomes after discontinuing them. Clin Mol Hepatol 2018; 24:374-383

Siberry, 2012

Siberry Safety of tenofovir use during pregnancy: early growth outcomes in HIV-exposed uninfected infants. AIDS 2012; 26:1151-9

Sibiude, 2014

Sibiude Association between prenatal exposure to antiretroviral therapy and birth defects: an analysis of the French perinatal cohort study (ANRS CO1/CO11). PLoS Med. 2014; 11:e1001635

Sibiude, 2019

Sibiude Liver Enzyme Elevation in Pregnant Women Receiving Antiretroviral Therapy in the ANRS-French Perinatal Cohort. J. Acquir. Immune Defic. Syndr. 2019; 81:83-94

The EPPICC study group, 2019

The EPPICC study group Nucleoside reverse transcriptase inhibitor backbones and pregnancy outcomes. AIDS 2019; 33:295-304

Torre, 2016

Torre Newborn Hearing Screenings in Human Immunodeficiency Virus-Exposed Uninfected Infants. J AIDS Immune Res 2016; 1:

Vigano, 2011

Vigano In utero exposure to tenofovir disoproxil fumarate does not impair growth and bone health in HIV-uninfected children born to HIV-infected mothers. Antivir. Ther. (Lond.) 2011; 16:1259-66

Wakano (Controls exposed to lamivudine), 2018

Wakano Antiviral therapy for hepatitis B virus during second pregnancies. J. Obstet. Gynaecol. Res. 2018; 44:566-569

Wakano (Controls unexposed, sick), 2018

Wakano Antiviral therapy for hepatitis B virus during second pregnancies. J. Obstet. Gynaecol. Res. 2018; 44:566-569

Watts, 2004

Watts Assessing the risk of birth defects associated with antiretroviral exposure during pregnancy. Am. J. Obstet. Gynecol. 2004; 191:985-92

Wilkinson, 2013

Wilkinson Cardiac biomarkers in HIV-exposed uninfected children. AIDS 2013; 27:1099-108

Williams, 2015

Williams Congenital anomalies and in utero antiretroviral exposure in human immunodeficiency virus-exposed uninfected infants. JAMA Pediatr 2015; 169:48-55

Williams, 2020

Williams Association of maternal antiretroviral use with microcephaly in children who are HIV-exposed but uninfected (SMARTT): a prospective cohort study. Lancet HIV 2020; 7:e49-e58

Williams, 2016

Williams Antiretroviral exposure during pregnancy and adverse outcomes in HIV-exposed uninfected infants and children using a trigger-based design. AIDS 2016; 30:133-44

Zash, 2016

Zash Reassuring Birth Outcomes With Tenofovir/Emtricitabine/Efavirenz Used for Prevention of Mother-to-Child Transmission of HIV in Botswana. J. Acquir. Immune Defic. Syndr. 2016; 71:428-36

Zash (Controls exposed to other treatments), 2017

Zash Comparative Safety of Antiretroviral Treatment Regimens in Pregnancy. JAMA Pediatr 2017; 171:e172222

Zash (Controls unexposed, disease free), 2017

Zash Comparative Safety of Antiretroviral Treatment Regimens in Pregnancy. JAMA Pediatr 2017; 171:e172222

Zash (Controls unexposed, sick), 2017

Zash Comparative Safety of Antiretroviral Treatment Regimens in Pregnancy. JAMA Pediatr 2017; 171:e172222

Zeng (Controls exposed to telbivudine), 2019

Zeng Effectiveness of tenofovir or telbivudine in preventing HBV vertical transmission for pregnancy. Medicine (Baltimore) 2019; 98:e15092

Zeng (Controls unexposed, sick), 2019

Zeng Effectiveness of tenofovir or telbivudine in preventing HBV vertical transmission for pregnancy. Medicine (Baltimore) 2019; 98:e15092