Carvedilol (versus unexposed) updated on 12-17-2024

Table   Graphic     exposition period:

Congenital malformations
Adverse outcome OR 95%CII2k No. casesNo. exposedpublication biasROBE-value
All congenital malformations (majors, minors, majors and minors, or unspecified)39.89 [0.79, 2010.55]-1 study4,0541not evaluable ROB-
Major congenital malformations39.89 [0.79, 2010.55]-1 study4,0541not evaluable ROB-

Growth parameters and prematurity
Adverse outcome OR 95%CII2k No. casesNo. exposedpublication biasROBE-value
Small for gestational age (weight)2.36 [0.83, 6.69]0%2 studies2345not evaluable ROB-
Preterm (< 37 weeks)2.02 [0.56, 7.31]-1 study2213not evaluable ROB-

Maternal consequences
Adverse outcome OR 95%CII2k No. casesNo. exposedpublication biasROBE-value
Caesarean9.34 [3.23, 26.99]0%2 studies22645not evaluable ROB18.16 [5.91; .]
Assisted deliveries (forceps, vacuum, ...)0.63 [0.03, 11.39]-1 study632not evaluable ROB-

Neonatal disorders
Adverse outcome OR 95%CII2k No. casesNo. exposedpublication biasROBE-value
Neonatal death (< 28 days of life)7.96 [0.15, 419.18]-1 study13not evaluable ROB-

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