Oxprenolol (versus unexposed) updated on 12-17-2024

Table   Graphic     exposition period:

Congenital malformations
Adverse outcome OR 95%CII2k No. casesNo. exposedpublication biasROBE-value
Cleft lip with or without cleft palate4.20 [1.78, 9.90]-1 study1,37447not evaluable ROB7.87 [2.96; .]
Cleft palate3.60 [1.10, 11.74]-1 study60153not evaluable ROB6.66 [1.44; .]
Neural Tube Defects1.40 [0.20, 9.90]-1 study1,20224not evaluable ROB-

Maternal consequences
Adverse outcome OR 95%CII2k No. casesNo. exposedpublication biasROBE-value
Caesarean1.52 [0.64, 3.62]-1 study2650not evaluable ROB-

Neonatal disorders
Adverse outcome OR 95%CII2k No. casesNo. exposedpublication biasROBE-value
Low Apgar score (< 7) (at 5 min)0.63 [0.06, 6.24]-1 study449not evaluable ROB-
Neonatal bradycardia2.22 [1.09, 4.51]-1 study5349not evaluable ROB3.86 [1.41; .]

Intrauterine deaths
Adverse outcome OR 95%CII2k No. casesNo. exposedpublication biasROBE-value
Early intrauterine death (< 22 weeks)5.91 [0.24, 147.74]-1 study150not evaluable ROB-
Late intrauterine deaths (> 22 weeks)0.38 [0.02, 8.02]-1 study250not evaluable ROB-

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