Verapamil (versus unexposed)

Table   Graphic     exposition period:

Congenital malformations
Adverse outcome OR 95%CII2k No. casesNo. exposedpublication biasROBE-value
All congenital malformations (majors, minors, majors and minors, or unspecified)2.51 [1.01, 6.28]-1 study3956not evaluable ROB4.46 [1.08; .]
3 non statistically significant endpoints reported in only one study

Growth parameters and prematurity
Adverse outcome OR 95%CII2k No. casesNo. exposedpublication biasROBE-value
Preterm (< 37 weeks)2.69 [1.34, 5.44]60%2 studies5970not evaluable ROB4.83 [2.00; .]
Low birth weight (< 2500g)2.61 [1.58, 4.31]-1 study18not evaluable ROB4.66 [2.54; .]

Maternal consequences
Adverse outcome OR 95%CII2k No. casesNo. exposedpublication biasROBE-value
Caesarean1.76 [1.21, 2.55]-1 study43not evaluable ROB2.92 [1.72; .]

Neonatal disorders
Adverse outcome OR 95%CII2k No. casesNo. exposedpublication biasROBE-value
1 non statistically significant endpoints reported in only one study

Intrauterine deaths
Adverse outcome OR 95%CII2k No. casesNo. exposedpublication biasROBE-value
3 non statistically significant endpoints reported in only one study