Interferon beta 1a (IFN-β1a)

Table   Graphic     exposition period:

Congenital malformations
Adverse outcome VerdictOR 95%CI I2k No. casesNo. exposedpublication bias
All congenital malformations (majors, minors, majors and minors, or unspecified)--0 study
Major congenital malformations--0 study
Congenital cataract--0 study

Growth parameters and prematurity
Adverse outcome VerdictOR 95%CI I2k No. casesNo. exposedpublication bias
preterm (< 37 weeks)1.16 [0.45, 2.99]63%3 studies249292not evaluable

Maternal consequences
Adverse outcome VerdictOR 95%CI I2k No. casesNo. exposedpublication bias
Preeclampsia--0 study
1 non statistically significant endpoints reported in only one study

Neonatal disorders
Adverse outcome VerdictOR 95%CI I2k No. casesNo. exposedpublication bias
1 non statistically significant endpoints reported in only one study

Long term consequences
Adverse outcome VerdictOR 95%CI I2k No. casesNo. exposedpublication bias
Children infections3.75 [1.00, 14.02]-1 study1029not evaluable

Intrauterine deaths
Adverse outcome VerdictOR 95%CI I2k No. casesNo. exposedpublication bias
Intrauterine deaths (as a whole)0.73 [0.41, 1.31]0%2 studies71292not evaluable
1 non statistically significant endpoints reported in only one study