Fingolimod

Table   Graphic     exposition period:

Congenital malformations
Adverse outcome VerdictOR 95%CI I2k No. casesNo. exposedpublication bias
Major congenital malformations0.85 [0.06, 12.12]30%2 studies674not evaluable
1 non statistically significant endpoints reported in only one study

Growth parameters and prematurity
Adverse outcome VerdictOR 95%CI I2k No. casesNo. exposedpublication bias
preterm (< 37 weeks)1.32 [0.47, 3.69]0%2 studies19250not evaluable

Intrauterine deaths
Adverse outcome VerdictOR 95%CI I2k No. casesNo. exposedpublication bias
Elective termination of pregnancy0.88 [0.16, 4.97]75%3 studies82136not evaluable
Early intrauterine death (< 22 weeks)0.77 [0.30, 2.00]0%2 studies28124not evaluable
2 non statistically significant endpoints reported in only one study