metaPreg - Fingolimod during pregnancy

Fingolimod

Table Graphic exposition period:

Adverse outcome	OR 95%CI	I2	k	No. cases	No. exposed	publication bias	ROB	E-value
Congenital malformations
Major congenital malformations	0.85 [0.06, 12.12]	30%	2 studies	6	74	not evaluable	ROB	-
1 non statistically significant endpoints reported in only one study
Growth parameters and prematurity
Adverse outcome	OR 95%CI	I2	k	No. cases	No. exposed	publication bias	ROB	E-value
Preterm (< 37 weeks)	1.32 [0.47, 3.69]	0%	2 studies	192	50	not evaluable	ROB	-
Intrauterine deaths
Adverse outcome	OR 95%CI	I2	k	No. cases	No. exposed	publication bias	ROB	E-value
Elective/induced termination of pregnancy	0.88 [0.16, 4.97]	75%	3 studies	82	136	not evaluable	ROB	-
Early intrauterine death (< 22 weeks)	0.77 [0.30, 2.00]	0%	2 studies	28	124	not evaluable	ROB	-
2 non statistically significant endpoints reported in only one study